植物雌激素的抗癌和抗氧化活性研究进展

S. Widyarini
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引用次数: 3

摘要

异黄酮类化合物包括一组具有有益的生物活性的植物雌激素,包括雌激素、抗氧化和抗癌。作为人类的膳食成分,它们可以从豆科蔬菜(如大豆中的染料木素)中生物利用,并且有充分的证据表明它们对健康有许多好处。广泛的人类流行病学研究和有限的动物研究已经确定异黄酮是一种潜在的化学预防剂,可以预防激素依赖性癌症。因此,本文就异黄酮类植物雌激素体外和体内抑制肿瘤的机制进行综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Phyto-Oestrogens - Its Anticarcinogenic and Antioxidant Activity - A Review
The isoflavonoids comprise a group of phytooestrogens that have useful biological activities including oestrogenic, antioxidant and anticancer. As dietary components for humans, they are bioavailable from leguminous vegetables (such as genistein from soybean), and have been well-documented to have numerous health benefits. A wide range of epidemiological studies in humans and limited studies in animals have identified isoflavonoids as a potential chemopreventive agents against hormone-dependent cancers. Therefore, this review focuses on the mechanisms of isoflavonoid phyto-oestrogens in inhibiting cancer in vitro and in vivo in the models of human cancers.
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