植入前基因诊断对人类胚胎的影响

Q4 Veterinary
Spermova Pub Date : 2016-12-26 DOI:10.18548/aspe/0004.02
Javier García-Ferreyra
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引用次数: 0

摘要

染色体异常在人类卵母细胞和胚胎中极为常见,并且与自然周期和使用辅助生殖技术的各种负面结果相关。非整倍体胚胎可能无法植入子宫,流产或导致儿童出现严重的医疗问题(例如,唐氏综合症)。胚胎植入前遗传学诊断(PGD)是一种检测胚胎非整倍体的技术,通过确保选择用于移植的胚胎染色体正常,以改善辅助生殖治疗的临床结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impacto del diagnóstico genético preimplantacional en embriones humanos
Chromosome abnormalities are extremely common in human oocytes and embryos and are associated with a variety of negative outcomes for both natural cycles and those using assisted reproduction techniques. Aneuploidies embryos may fail to implant in the uterus, miscarry, or lead to children with serious medical problems (e.g., Down syndrome). Preimplantation genetic diagnosis (PGD) is a technique that allows the detection of aneuploidy in embryos and seeks to improve the clinical outcomes od assisted reproduction treatments, by ensuring that the embryos chosen for the transfer are chromosomally normal.
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来源期刊
Spermova
Spermova Veterinary-Veterinary (miscellaneous)
CiteScore
0.30
自引率
0.00%
发文量
24
审稿时长
9 weeks
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