乳房再造的创新与进步

E. Chang
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引用次数: 0

摘要

近年来,乳房重建领域在乳房保护和乳房切除术后重建方面取得了巨大的进步。肿瘤整形手术领域已经迅速成为护理的标准,在美容整形手术领域中根深蒂固的技术现在被用来为接受部分乳房切除术的患者提供最理想的重建手段。然而,其他技术,包括局部蒂皮瓣以及脂肪移植或脂肪填充也成为有用的辅助手段,以改善这些患者的整体美容效果。对于乳房切除术后进行重建的患者,新技术不断涌现,以优化使用假体为基础的重建方法,不仅在设备本身方面,而且在手术技术方面,特别是脱细胞真皮基质(ADM)。ADM的频繁使用开创了假体回到皮下或胸前位置的时代,这在以前是一个高并发症的困扰,包括包膜挛缩。检验这种方法的早期研究已经证明了高满意度和有希望的结果。然而,正如乳房重建的有益发展一样,争议也随之而来,其中最普遍的是对乳房植入物相关间变性大细胞淋巴瘤与纹理装置相关的描述。自体重建领域也取得了巨大的进步,其中游离组织移植已迅速成为重建的金标准手段。然而,尽管以前腹部供体部位是自体重建的唯一手段,但随着穿支皮瓣和微血管手术的舒适度提高,包括大腿和腰椎在内的新型供体部位迅速受到欢迎。随着显微外科手术经验的增长,自由组织移植不再仅仅关注于获得一个可行的皮瓣,而是关注于优化患者的满意度和结果。通过神经化创造感觉皮瓣也很快变得司空见惯,但长期结果仍有待确定。最后,淋巴水肿超显微手术领域现在是乳腺癌患者接受治疗重建的关键组成部分。考虑到需要包括化疗和放疗在内的多模式治疗,再加上疾病晚期患者需要进行腋窝清扫,淋巴水肿的风险只会增加。两种生理技术,淋巴静脉旁路(LVB)和血管化淋巴结转移(VLNT)已被证明是非常有效的,并显著改变了乳腺癌相关淋巴水肿(BCRL)的治疗方法,并被证明是改善BCRL患者生活质量的有效手段。该系列文章的当前纲要旨在从该领域一些最知名的专家那里提供现代乳房重建中最新颖问题的全面概述。虽然该系列并不意味着详尽无遗,但文章的汇编旨在为读者提供有关乳房重建中一些主要主题的新技术,数据和研究的广泛概述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Novel innovations and advancements in breast reconstruction
The field of breast reconstruction has witnessed tremendous advancements over the years both in terms of breast conservation as well as reconstruction following a mastectomy. The field of oncoplastic surgery has quickly become the standard of care where techniques engrained in the field of cosmetic, aesthetic plastic surgery are now employed to provide the most optimal means of reconstruction for patients undergoing a partial mastectomy. However, other techniques including local pedicle flaps as well as fat grafting or lipofilling have also become useful adjuncts to improve the overall cosmetic results for these patients. For patients undergoing reconstruction following a mastectomy, new technologies are constantly emerging to optimize reconstruction using a prosthesis-based approach, not simply in terms of the devices themselves, but also in terms of surgical techniques and in particular acellular dermal matrices (ADM). The frequent use of ADM has ushered in an era where the prosthesis has returned to a subcutaneous or prepectoral location which was previously plagued with high complications including capsular contracture. Early studies examining this approach have demonstrated high satisfaction and promising results. However, just as there have been beneficial developments in breast reconstruction, so have controversies arisen, the most prevalent of which is the description of breast implant associatedanaplastic large cell lymphoma associated with textured devices. Tremendous advancements have also occurred in the arena of autologous reconstruction where free tissue transfer has quickly become the gold standard means of reconstruction. However, whereas previously the abdominal donor site was the only means of autologous reconstruction, novel donor sites including the thigh and lumbar region are quickly gaining in popularity with the increased comfort with perforator flaps and microvascular surgery. With the growing experience with microsurgery, free tissue transfer no longer focuses solely on achieving a viable flap, but on optimizing patient satisfaction and outcomes. The creation of a sensate flap through neurotization is also quickly becoming commonplace, but long-term outcomes remain to be determined. Finally, the field of lymphedema super microsurgery is now a critical component for reconstruction in patients undergoing treatment for breast cancer. Given the need for multimodality therapy including chemotherapy and radiation, coupled with the need for an axillary dissection in patients with more advanced disease, the risks of lymphedema are only expected to increase. The two physiologic techniques, the lymphovenous bypass (LVB) and vascularized lymph node transfer (VLNT) have proven to be remarkably effective and have dramatically altered the treatment for breast cancer related lymphedema (BCRL) and proven to be an effective means at improving the quality of life of patients suffering from BCRL. The current compendium of articles in the series on breast reconstruction aims to provide a comprehensive overview of the most novel issues in breast reconstruction in the modern era from some of the most world-renowned experts in the field. While the series is not meant to be exhaustive, the compilation of articles aims to provide the readership with a broad overview of novel techniques, data, and research on some of the premier topics in breast reconstruction.
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