建立病毒感染行为模型,评估感染引发社会灾难的对策

Q4 Engineering
Haruhisa Sakamoto, H. Ujiié
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引用次数: 0

摘要

应根据流行病学确定的感染特征,合理制定和实施新发疾病的感染控制和防护措施。为了响应这一需求,本研究提出了病毒感染在社会中传播过程的数学模型。此外,将该模型应用于新型冠状病毒COVID-19的传播病例。结果表明:病毒感染的进展可以简单地用日速率基本繁殖数r和感染检出率k来建模;r由流行病学确定的基本繁殖数Ro和病毒感染期T决定;每日有效繁殖数reff可定义为reff = r(1 - k), reff < 1表示感染受到抑制;可实现感染抑制,使k大于流行病学参数对应的临界值KCR;该模型较好地拟合了COVID-19的实际感染行为,可以对感染抑制措施进行定量评价;就中国而言,彻底的检测和隔离可以在10天后将感染状况改善到抑制阶段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modeling of viral infection behavior to evaluate countermeasures against infection causing social disaster
Infection control and protection from the emerging diseases should be rationally formulated and operated based on epidemiologically determined infection characteristics. In order to respond to this requirement, this study proposes a mathematical model of the progression of the spread of viral infection in the society. In addition, the model was applied to cases of transmission of the new coronavirus COVID-19. From the results, the following is clarified: the progress of the viral infection can be simply modeled by the daily-rate basic reproduction number r and the infection detection rate k; r is determined by the epidemiologically determined values of basic reproduction number Ro and the infection lifetime T of virus; the dailyrate effective reproduction number reff can be defined by reff = r(1 – k), and reff < 1 indicates that the infection is suppressed; the infection suppression can be realized to make k greater than the critical value kcr corresponding to the epidemiological parameters; this model fits well with the practical infection behavior of COVID-19 and enables the quantitative evaluation of infection suppress measures; In the case of China, thorough detecting and isolation would have improved the infection condition to the suppression phase after only 10 days.
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来源期刊
Journal of Biorheology
Journal of Biorheology Engineering-Mechanical Engineering
CiteScore
0.50
自引率
0.00%
发文量
5
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