犬乳腺肿瘤与潜在危险因素和生存时间的组织学关联

IF 0.2 4区 农林科学 Q2 Veterinary
Y. Salas, E. Aburto, R. A. Alonso, A. Márquez, Hortensia Corona, L. Romero
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引用次数: 2

摘要

犬乳腺肿瘤的流行病学和临床病理特征可能为促进疾病行为的分析提供有价值的信息,并代表了研究女性乳腺癌的潜在工具。本研究的目的是将犬乳腺肿瘤的组织学特征与潜在的危险因素和生存率联系起来。从80只母狗身上收集了178个乳腺肿瘤。统计分析包括一系列单变量研究和不同研究变量的频率,如卡方检验(x2)的双变量分析、相对风险和Kaplan Meier生存分析,以及用于将肿瘤生物学行为与狗的品种联系起来的多重对应分析。大多数患者年龄大于8岁,至少有一个恶性肿瘤,通常是孤立的,测量大于6厘米;这些患者的存活率很低。最常见的肿瘤是复杂腺瘤、良性混合瘤、复杂癌和混合型癌。最常见的患病品种是贵宾犬、可卡犬和腊肠犬,而患肿瘤风险最高的品种是可卡犬、拉布拉多猎犬和德国牧羊犬。总的来说,这些数据表明,狗的乳腺肿瘤主要影响患有恶性肿瘤的老年雌性,死亡率和短期存活率都很高。然而,最常受影响的品种并不一定是最易受影响的。我们的数据不支持在未生育的雌性犬中增加犬乳腺肿瘤风险的假设。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Asociación histológica con factores potenciales de riesgo y tiempo de sobrevida en el tumor mamario canino
The epidemiological and clinicopathological features of canine mammary tumors may provide valuable information to facilitate analysis of the behavior of the disease and represent a potential tool for the study of breast cancer in women. The aim of this study was to associate the histological features of canine mammary tumors with potential risk factors and survival. One hundred and seventy-eight mammary tumors were collected from 80 female dogs. The statistical analyses consisted of a series of univariate studies and frequencies of the different study variables, such as a bivariate analysis with the Chi squared test ( X 2 ), a relative risk and Kaplan Meier survival analysis, and a multiple correspondence analysis was used to correlate the tumor’s biological behavior with the dogs’ breed. Most patients were older than 8 years and had at least one malignant tumor, which was usually solitary and measured more than 6 cm; these patients had poor survival. The most frequent tumors were a complex adenoma, benign mixed tumor, carcinoma complex and mixed type carcinoma. The most commonly affected breeds were Poodle, Cocker Spaniel and Dachshund, and the breeds at the highest risk of tumor development were Cocker Spaniel, Labrador Retriever and German Shepherd. Overall, the data indicated that mammary tumors in dogs mainly affected older females with malignant tumors and that there were high mortality and short-term survival rates. However, the most commonly affected breeds were not necessarily the most susceptible. Our data do not support the hypothesis of an increased risk of canine mammary tumors in nulliparous female dogs.
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来源期刊
Veterinaria Mexico
Veterinaria Mexico VETERINARY SCIENCES-
自引率
0.00%
发文量
0
审稿时长
>12 weeks
期刊介绍: Veterinaria México OA (ISSN 2448-6760) is an online scientific journal edited by Universidad Nacional Autónoma de México (UNAM). The journal is Open Access and follows UNAM''s initiative, to transmit knowledge free of charge to the readership and authors, with no Article Processing Charges. This journal publishes advances in Veterinary Sciences and Animal Production, and to reach more lectures across the world the journal was updated since 2014 from its predecessor printed in paper Veterinaria México (ISSN 0301-5092) and its digital version (ISSN 2007-5472).
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