乳腺癌患者化疗期间吸白水冰片与薄荷提取物冰片对恶心呕吐的影响比较

Hamid Robat Sarpooshi, Mohammd Haddadi, Maz, arani Ms, R. Borghabani
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引用次数: 0

摘要

背景和目的:乳腺癌被认为是妇女中最普遍认识和最致命的疾病。包括手术、放疗和化疗在内的各种策略被用于治疗癌症。化疗作为一种典型的治疗策略,会带来各种生理和心理症状。恶心和呕吐是化疗最常见的公认症状之一。尽管抗恶心和抗呕吐药物取得了进展,但恶心和呕吐仍然是化疗最普遍的反应。一方面,替代和补充药物属于基本和安全措施。本研究比较了白开水冰片和薄荷浓缩液冰片对化疗期间恶心呕吐的影响。材料与方法:本临床研究将90例接受化疗的乳腺癌患者随机分为“对照组”、“白开水冰块”和“薄荷提取物冰块”三组。“加清水冰块”组、“加薄荷提取物冰块”组和“对照组”分别给予30块1cc冰块、30块1cc薄荷提取物冰块和30毫升水;分别。恶心程度以VAS数值量表评定,呕吐程度以频率评定。应用SPSS16软件对数据进行分析。结果表明:“白开水冰粒”干预组、“薄荷提取物冰粒”干预组和“对照组”干预组的平均得分分别为1.6、1.96和2.9;“白开水冰块组”和“薄荷提取物冰块组”干预组呕吐次数分别为0.2、0.233次,对照组平均呕吐次数为0.266次,无显著性意义(p值:0.835)。结论:根据研究结果,白开水冰片和薄荷提取物冰片对恶心有缓解作用,而对化疗引起的呕吐没有作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Comparison of Sucking Ice Bits With Plain Water and Ice Bits Containing of Mint Extract on Nausea and Vomiting During Chemotherapy in Patients Suffering from Breast Cancer
Background and purpose: Breast cancer is known as the most widely recognized and lethal disease among women. Various strategies including surgery, radiotherapy, and chemotherapy are applied to cure cancer. Chemotherapy, as a typical helpful strategy, brings about various physical and mental symptoms. Nausea and vomiting are amongst the most common widely recognized symptoms of chemotherapy. Regardless of advancement in anti-nausea and anti-vomiting medicines, nausea and vomiting are yet the most widely recognized reactions of chemotherapy. In one hand, alternative and complementary medicines are among basic and safety measurements. This study has been accomplished to compare the effect of sucking ice bits with plain water and ice bits containing of mint concentrate on nausea and vomiting during chemotherapy. Materials and methodology: In this clinical study, 90 patients suffering from breast cancer with chemotherapy were placed into three groups of "control", "ice bits with plain water", and "ice containing of mint extract" randomly. Thirty ice bits in 1cc, 30 ice bits with mint extract in 1cc, and 30 cc of water were given to "ice bits with plain water", "ice bits containing mint extract", and "control" groups; respectively. Nausea was assessed by numerical scale of VAS, and vomiting was evaluated based on frequency. SPSS16 software was applied to analyze data. Findings: The findings showed that intervention group of "ice bits with plain water", "ice bits containing of mint extract", and "control" groups have got averages of 1.6, 1.96, and 2.9; respectively indicating to significance (P-value: 0.010), while in "ice bits with plain water" and in intervention group of "ice containing of mint extract" group there are 0.2, 0.233 vomiting cases, so that an average of 0.266 vomiting was observed in the control group indicating to a lack of significance (P-value: 0.835). Conclusion: According to the study results, sucking ice bits with plain water and ice bits containing of mint extract can take effect on nausea while they make no effect on vomiting resulted from chemotherapy.
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