MDMA对青春期大鼠的急性和长期行为影响

The open addiction journal Pub Date : 2011-03-29 DOI:10.2174/1874941001104010042

E. Remmelink, I. McGregor

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引用次数: 0

摘要

急性MDMA，即使是低剂量，也会增加成年大鼠b[1]的社交互动，而长期服用则会导致社交互动减少，焦虑增加和物体识别记忆受损[2,3]。本研究探讨MDMA对青春期大鼠是否有同样的作用。此外，我们还研究了青春期大鼠对MDMA的偏好是否受社会环境的调节。

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Acute and Long-Term Behavioural Effects of MDMA in Adolescent Rats

Acute MDMA, even at low doses, increases social interaction in adult rats [1] while on the long-term its consumption produces a decrease in social interaction, an increase in anxiety and impaired object recognition memory [2, 3]. This study investigated whether MDMA has the same effects in adolescent rats. Additionally, we investigated whether the preference of adolescent rats for MDMA was mediated by social context.

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The open addiction journal

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