糖尿病成人轻度抑郁筛查的重要性

K. Wilhelm, J. Reddy, J. Crawford, L. Robins, L. Campbell, J. Proudfoot
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引用次数: 8

摘要

目的:虽然重度抑郁症对糖尿病的影响越来越受到关注,但轻度抑郁症的作用却没有得到很好的研究。这项观察性研究比较了三组患有1型(T1DM)或2型(T2DM)糖尿病的成年人:i)无抑郁症状(NODEP), ii)轻度抑郁症状(mild)和iii)中度至重度症状(MOD/重度)-糖尿病困扰,心理困扰,焦虑和躯体症状,生活质量和HbA1c水平。方法:245例参加两家医院糖尿病门诊的患者(27%为T1DM;73%的T2DM患者完成了自我报告测量,包括患者健康问卷(PHQ)、糖尿病问题领域(PAID)量表和简短健康调查(SF12)。精神科医生对参与者进行了访谈,并记录了他们的糖化血红蛋白水平。结果:半数患者在PHQ-9上报告抑郁症状(MILD组29%,MOD/重度组21%,NODEP组50%)。与NODEP组相比,MILD组参与者的糖尿病困扰、心理困扰、焦虑和躯体症状水平显著升高,与心理健康相关的生活质量显著降低。与其他两组相比,MOD/SEVERE组的参与者有更高水平的糖尿病困扰、心理困扰、焦虑和躯体症状,而且生活质量明显较低。两组HbA1c无显著差异。结论:轻度抑郁症状在糖尿病患者中很常见,并与较高水平的糖尿病困扰、心理困扰、焦虑和躯体症状以及较低的生活质量相关。解决轻度抑郁为预防糖尿病患者的临床抑郁提供了一条潜在的途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Importance of Screening for Mild Depression in Adults with Diabetes
Aim: While the impact of major depression on diabetes has gained increasing attention, the role of minor depression is less well investigated. This observational study compared three groups of adults with Type 1 (T1DM) or Type 2 (T2DM) diabetes mellitus: with me) no depressive symptoms (NODEP), ii) mild depressive symptoms (MILD) and iii) moderate-to-severe symptoms (MOD/SEVERE)-on diabetes distress, psychological distress, anxiety and somatic symptoms, quality of life and HbA1c levels. Methods: 245 outpatients attending two hospital diabetes services (27% with T1DM; 73% with T2DM) completed self-report measures including patient health questionnaire (PHQ), problem areas in diabetes (PAID) scale and short form health survey (SF12). Participants were interviewed by a psychiatrist and HbA1c levels recorded. Results: Half the sample reported depressive symptoms on the PHQ-9 (29% in the MILD group, 21% in MOD/ SEVERE and the remaining 50% in the NODEP group). Compared to the NODEP group, MILD group participants had significantly higher levels of diabetes distress, psychological distress, anxiety and somatic symptoms and significantly lower mental-health related quality of life. Participants in the MOD/SEVERE group had significantly higher levels of diabetes distress, psychological distress, anxiety, and somatic symptoms than either of the other two groups, and significantly lower quality of life. The groups did not differ significantly on HbA1c. Conclusions: Mild symptoms of depression in patients with diabetes are common and are associated with higher levels of diabetes distress, psychological distress, anxiety and somatic symptoms and lower quality of life. Addressing mild depression provides a potential avenue for preventing clinical depression in patients with diabetes.
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