γ射线辐照下壳聚糖、胶原蛋白及壳聚糖/胶原蛋白共混膜的吸水性能

Q4 Pharmacology, Toxicology and Pharmaceutics
F. Lukitowati, D. J. Indrani
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引用次数: 10

摘要

本研究考察了γ射线辐照下壳聚糖、胶原蛋白和壳聚糖/胶原蛋白混合膜的吸水率。这些膜是通过溶剂蒸发法制备的。然后所有的膜都接受15或25千吉γ射线剂量的照射,而未照射的膜作为对照。将膜浸泡在蒸馏水中180分钟后,通过计算重量增加百分比来测定吸水率。结果表明,不同的膜和辐照剂量对吸水曲线有不同的影响。然而,60 min后,所有的吸水曲线趋于平稳。从膜的类型来看,壳聚糖膜的吸水率最高,共混膜的吸水率最低,胶原膜的吸水率居中。当使用较高的辐射剂量时,壳聚糖膜的吸水性降低,混合膜也是如此,但胶原蛋白膜却没有。综上所述,经γ射线照射和不经γ射线照射后,壳聚糖、胶原蛋白和壳聚糖/胶原蛋白共混膜的吸水率先稳定增加后趋于稳定。辐照共混膜的吸水率最低;然而,这些数值相对稳定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Water Absorption of Chitosan, Collagen and Chitosan/Collagen Blend Membranes Exposed to Gamma-ray Irradiation
TThis study investigated the water absorption of chitosan, collagen, and chitosan/collagen blend membranes exposed to gamma-ray irradiation. These membranes were produced via the solvent evaporation method. All membranes then underwent irradiation at 15 or 25 kGy gamma-ray doses, while membranes without irradiation were used as controls. After immersing the membranes in distilled water for up to 180 min, water absorption was determined by calculating the percentage weight increase. The results showed changes in the water absorption curves with differing membranes and irradiation doses. However, after 60 min, all of the water absorption curves plateaued. With respect to membrane type, chitosan membranes exhibited the highest water absorption, the blend displayed the lowest, and collagen was in the mid range. With the use of higher radiation doses, chitosan membranes displayed lower water absorption, which was also true of the blend but not collagen membranes. To conclude, the water absorption of chitosan, collagen, and chitosan/collagen blend membranes with and without gamma-ray irradiation initially increased steadily and then plateaued. The water absorption values of the irradiated blend membranes were the lowest; however, the values were relatively steady.
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来源期刊
Iranian Journal of Pharmaceutical Sciences
Iranian Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
0.50
自引率
0.00%
发文量
0
期刊介绍: Iranian Journal of Pharmaceutical Sciences (IJPS) is an open access, internationally peer-reviewed journal that seeks to publish research articles in different pharmaceutical sciences subdivisions: pharmacology and toxicology, nanotechnology, pharmaceutics, natural products, biotechnology, pharmaceutical chemistry, clinical pharmacy and other pharmacy related topics. Each issue of the journal contents 16 outstanding research articles in area of pharmaceutical sciences plus an editorial written by the IJPS editors on one of the most up to date advances topics in pharmacy. All articles published by IJPS would be permanently accessible online freely without any subscription charges. Authors of the published articles have granted the right to use and disseminate their article to third parties.
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