系统分析电磁辐射对空间医学目标热休克基因表达的影响

Q4 Biochemistry, Genetics and Molecular Biology

Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine Pub Date : 2023-01-01 DOI:10.21687/0233-528x-2023-57-2-5-13

А. Artamonov, D. Molodtsova, T.A. Smirnova, N. Konstantinova

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引用次数: 0

摘要

利用科学出版物对电磁辐射(EMR)对各种生物体内热休克基因表达的影响进行了系统的分析。国际规范性文件假设高强度EMR(100µWatt/cm2)会导致热休克基因的表达和随之而来的生物后果。在俄罗斯，通量能量数据水平为10µWatt/cm2。术语“数据级”是指EMR生物效应本质上不是热效应。但是，俄罗斯国家标准GOST R 50804-95载有对载人航天器中宇航员环境的一般医疗工程要求，将0.3-300 GHz EMR频段内的最大允许电平定为1000µWatt/cm2。系统分析该波段的EMR效应并没有揭示热休克基因的表达。研究应重点关注EMR的非热生物效应。

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SYSTEMATIC ANALYSIS OF THE ELECTROMAGNETIC RADIATION EFFECT ON EXPRESSION OF THE HEAT SHOCK GENE WITH REGARD TO THE GOALS OF SPACE MEDICINE

Scientific publications were used to undertake systematic analysis of the effects of electromagnetic radiation (EMR) on heat shock gene expression in various bio-objects. International normative documents assume that high intensity EMR (100 µWatt/cm2) causes expression of the heat shock gene and ensuing biological consequences. In Russia, the flux energy data level is taken to be 10 µWatt/cm2. Term "data level" means that the EMR bio-effect is not thermal by nature. However, Russian national standard GOST R 50804-95 containing the general medical-engineering requirements to cosmonaut's environment in a piloted spacecraft sets the maximum admissible level at 1000 µWatt/cm2 within the EMR band of 0.3–300 GHz. Systematic analysis of the EMR effects within this band did not reveal expression of the heat shock gene. The investigation should be proceeded with the focus on the EMR non-heat bio-effects.

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来源期刊

Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

0.60

自引率

0.00%

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