De Ritis检测肿瘤的术前血细胞计数指标和预测位置

Hakan Bahadır Haberal, Kubilay Sarikaya, Fahri Erkan Sadioğlu, Muhammed Arif İbiş, Çağrı Şenocak, Ö. Bozkurt
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引用次数: 1

摘要

目的:探讨术前全血及生化指标中的中性粒细胞-淋巴细胞比值(NLR)、血小板-淋巴细胞比值(PLR)、淋巴细胞-单核细胞比值(LMR)、全身免疫-炎症指数(SII)及De-Ritis比值对睾丸肿瘤的诊断价值。材料与方法:回顾性分析我院2010年10月至2019年12月行腹股沟睾丸切除术治疗睾丸肿瘤的患者及行精索静脉曲张切除术作为对照组的患者资料。资料缺失、年龄在18岁以下或有额外发病率的患者被排除在本研究之外。测定NLR、PLR、LMR、SII指数和De-Ritis比值的预测值,并探讨这些参数对睾丸肿瘤的诊断价值。结果:本组患者行腹股沟睾丸切除术34例(14.1%),行精索静脉曲张切除术207例(85.9%)。手术患者中位年龄为27(23-32)岁。精原细胞瘤18例(52.9%),混合生殖细胞瘤12例(35.3%),卵黄囊瘤3例(8.8%),胚胎癌1例(2.9%)。61.8%的睾丸肿瘤处于T2期,35.3%的患者有转移。NLR、PLR、LMR和SII指数的临界值分别为1.76、133.43、7.81和571.63。De-Ritis ratio的临界值无统计学意义(p = 0.183)。多因素分析中预测睾丸肿瘤的唯一显著因素是SII指数(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preoperatif tam kan sayımı belirteçleri ve De-Ritis oranının testis tümörünün tanısındaki prediktif yeri
Aim: To determine the value of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), systemic immune-inflammation (SII) index and De-Ritis ratio, which are among preoperative whole blood and biochemical parameters, in the diagnosis of testicular tumor. Materials and Methods: The data of patients who underwent inguinal orchiectomy for testicular tumor in our clinic between October 2010 and December 2019 and patients who underwent varicocelectomy, as a control group, were retrospectively analyzed. Patients with missing data, under 18 years of age or with additional morbidity were excluded from the present study. Prediction values for NLR, PLR, LMR, SII index and De-Ritis ratio were determined and the value of these parameters in the diagnosis of testicular tumor was examined. Results: Thirty-four (14.1%) patients underwent inguinal orchiectomy while 207 (85.9%) patients underwent varicocelectomy in the present study. The median age of the patients during surgery was 27 (23-32) years. The number of patients with seminoma, mixt germ cell tumor, yolk sac tumor and embryonal carcinoma was 18 (52.9%), 12 (35.3%), 3 (8.8%) and 1 (2.9%), respectively. It was determined that 61.8% of the patients with testicular tumors were in the T2 stage and 35.3% had metastasis. The cut-off values for NLR, PLR, LMR and SII index were determined as 1.76, 133.43, 7.81 and 571.63, respectively. There was no statistically significant cut-off value for De-Ritis ratio (p = 0.183). The only significant factor for predicting testicular tumor was SII index in multivariate analysis (p
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