钬激光治疗扩散至输尿管口的膀胱尿路上皮癌

IF 0.1 Q4 ONCOLOGY
M. Е. Novikov, N. A. Meleshko, I. Akopyan
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引用次数: 1

摘要

在发达国家,尿路上皮移行细胞癌是第四大最常见的癌症。就发病率而言,仅次于前列腺癌、乳腺癌、肺癌和结直肠癌。在绝大多数病例中,尿路上皮癌发生于膀胱。它占所有尿路移行细胞癌病例的90 - 95%。更罕见的是,5 - 10%的患者必须处理其定位在上尿路(在盆腔系统或输尿管)。在17%的上尿路癌症中,膀胱癌同时被诊断出来。尿路上皮移行细胞癌的发病率在过去的几十年里随着诊断的提高和患者生存率的提高而增加。使用现代高科技设备进行可视化和直接手术干预有助于取得这样的结果。利用激光能量作为内镜肿瘤学组织剥离的主要工具,与传统的电手术相比,这种方法具有不可否认的优势。我们报告了输尿管浸润的尿路上皮性膀胱癌的诊断和手术治疗的临床观察。我们采用了一种经尿道输尿管浸润膀胱尿路上皮肿瘤切除术,采用整体激光。术中行输尿管镜检查,肿瘤未扩散到输尿管壁外的上尿路。由于铥激光对组织的精确作用,不是切除,而是实际上是解剖膀胱壁,获得了高质量的宏观准备,这使得建立最终诊断成为可能。组织学结论:来自膀胱的非侵袭性尿路上皮癌G2-3;左输尿管口-异型性尿路上皮内衬纤维组织碎片。术后3个月未发现尿路上皮癌复发,提示手术质量高。这一临床观察证明了激光整体解剖相对于膀胱肿瘤治疗的优越性。获得高质量的尿路上皮移行细胞癌的宏观产物有助于避免不合理的根治性肾输尿管切除术和进行器官保留治疗,无论是绝对指征还是选择性指征。1.94 μ m铥铒激光器是一种有效的工具,用于微创经尿道介入治疗非侵袭性膀胱癌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tulium laser in urothelial carcinoma of the bladder with spread to the ostium of the ureter
Urothelial transitional cell cancer in developed countries is the 4th most common. In terms of frequency, it is outstripped only by prostate, breast, lung, and colorectal cancer. In the vast majority of cases, urothelial carcinoma develops in the bladder. It accounts for 90—95 % of all cases of transitional cell cancer of the urinary tract. Much less often, in 5—10 % have to deal with its localization in the upper urinary tract (in the calico-pelvic system or ureter). In 17 % of upper urinary tract cancers, bladder cancer is simultaneously diagnosed. The incidence of urothelial transitional cell cancer has increased over the past few decades as a result of improved diagnosis and improved survival of patients with this nosology. The use of modern, high-tech equipment for visualization and direct surgical intervention contributes to such results. The use of laser energy as the main tool for tissue dissection in endoscopic oncourology reveals the undeniable advantages of this method in comparison with the traditional electrosurgery.We present a clinical observation of the diagnosis and surgical treatment of urothelial bladder cancer with invasion of the ureter, performed by en-bloc tulium laser. An operation was performed-transurethral resection of a urothelial bladder tumor with invasion of the ureter, performed by en-bloc tulium laser. Intraoperatively, ureteropieloscopy was performed, and the tumor did not spread to the upper urinary tract beyond the intramural part of the ureter. Thanks to the precision of the action of the tulium laser on the tissue, not resection, but, in fact, dissection of the bladder wall, a high-quality macropreparation was obtained, which made it possible to establish a final diagnosis. Histological conclusion: from the bladder — non-invasive urothelial cancer G2-3; from the mouth of the left ureter — fragments of fibrous tissue lined with urothelium from atypia. 3 months after the operation — no recurrence of urothelial cancer was revealed, which indicates a high quality of the operation.This clinical observation demonstrates the superiority of laser en-bloc dissection compared to the treatment of bladder tumors. Obtaining a macro-product of urothelial transitional cell cancer of the highest quality can contribute to avoiding unjustified radical nephrureterectomies and conducting organ-preserving treatment, for absolute and elective indications. The 1.94 µm Tulium Erbium laser is an effective tool for performing minimally invasive transurethral interventions in non-invasive bladder cancer.
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来源期刊
Onkourologiya
Onkourologiya ONCOLOGY-
CiteScore
0.40
自引率
0.00%
发文量
59
审稿时长
10 weeks
期刊介绍: The main objective of the journal "Cancer urology" is publishing up-to-date information about scientific clinical researches, diagnostics, treatment of oncologic urological diseases. The aim of the edition is to inform the experts on oncologic urology about achievements in this area, to build understanding of the necessary integrated interdisciplinary approach in therapy, alongside with urologists, combining efforts of doctors of various specialties (cardiologists, pediatricians, chemotherapeutists et al.), to contribute to raising the effectiveness of oncologic patients’ treatment.
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