皮质醇和covid -19给“压力激素”带来过度压力

Q4 Medicine

US endocrinology Pub Date : 2020-01-01 DOI:10.17925/USE.2020.16.2.66

R. Pal, M. Banerjee

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引用次数: 0

摘要

血清皮质醇是衡量潜在疾病严重程度的指标，疾病越严重，循环皮质醇水平越高，预后不良/死亡的机会越大。不足为奇的是，最近的一项研究发现，血清皮质醇水平较高与2019冠状病毒病(COVID-19)患者的预后不良有关。然而，该研究没有考虑COVID-19严重程度的混杂效应，因此，此外，根据血清皮质醇水平指导糖皮质激素治疗是一个不切实际的主张，迄今为止还没有强有力的证据支持。因此，对COVID-19患者进行常规血清皮质醇测量是徒劳的，不应鼓励©Touch Medical Media 2020

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cortisol and COVID-19—Putting Undue Stress on the “Stress Hormone”

Serum cortisol is a measure of underlying disease severity The more severe the disease, the higher the circulating cortisol levels and the greater the chances of poor prognosis/mortality Not surprisingly, a recent study found that higher serum cortisol was associated with poor prognosis in patients with coronavirus disease 2019 (COVID-19) Nevertheless, the study did not take into consideration the confounding effect of COVID-19 severity;hence, the results could not be regarded as being fully adjusted Besides, guiding glucocorticoid therapy based on serum cortisol levels is an impractical proposition, and to date is not backed by robust evidence Therefore, routine measurement of serum cortisol in patients with COVID-19 is a futile endeavor and should not be encouraged © Touch Medical Media 2020

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来源期刊

US endocrinology Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

1.90

自引率

0.00%

发文量