2-(3,5-二氧杂氮环[5.2.2.02,6]十一-8-烯-4-基)丙酸的合成及若干反应

Tatyana S. Оkovytaya, I. Tarabara
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引用次数: 3

摘要

以易获得的原料4-氧杂环[5.2.2.0 2,6]11 -8-烯-3,5-二酮为原料,合成了新型2-(3,5-二氧杂环[5.2.2.0 2,6]11 -8-烯-4-基)丙酸。研究了标题的化学反应性。特别是,它被转化为相应的酰氯和简单酰胺。酰基叠氮化物的Curtius重排产生异氰酸酯,然后转化为一系列多环脲。值得注意的是,叠氮化物的热重排过程没有受到母体化合物中存在的张力双键的干扰。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis and some reactions of 2-(3,5-dioxo-4-azatricyclo[5.2.2.02,6]undec-8-ene-4-yl)propanoic acid
Novel 2-(3,5-dioxo-4-azatricyclo[5.2.2.0 2,6 ]undec-8-ene-4-yl)propanoic acid was synthesized from easily accessible starting material, 4-oxatricyclo[5.2.2.0 2,6 ]undec-8-ene-3,5-dione. Chemical reactivity of the title was investigated. In particular, it was converted into the corresponding acyl chloride and simple amides. Curtius rearrangement of the acyl azide delivered an isocyanate, which was then transformed into a series of polycyclic ureas. Noteworthy, the thermal rearrangement of the azide underwent without interference from the strained double bond present in the parent compound.
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