纳米氧化铜作为点击反应的催化剂

Reda, Abdelhady, Mustafa, ElKhashab, Abdelaziz, Ahmed, Nayl, Elsayed, Mohamed, Badawy, TamerAbdelmoemen, Malah
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引用次数: 1

摘要

点击反应不是特定的反应,但它们是一种生产产品的方式,遵循自然界的例子,通过将小部分连接在一起,以良好的产量产生一个大分子。该反应的思想被用于生物分子合成、药理学和各种生物计量学应用。第一个咔嗒反应是铜化合物催化叠氮化物与炔(CuAAC)的反应,这种铜催化的“咔嗒”反应不需要金属上的基团,金属氧化物也可以加速反应。为了增强Click反应的产物,我们用制备的纳米铜化合物(NPs)取代了经典反应中的铜化合物。并测量原料的消耗量。这种演变的背后是纳米铜复合物(NPs)对H2O2的催化作用。由于纳米铜化合物(NPs)的表面积大,研究发现:纳米铜化合物(NPs)可以加速H2O2的分解,也可以加速经典的咔嗒反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nano-copper Oxide as Catalyst for Click Reactions
Click reactions are not specific reactions, but they are a way of generating products that follow examples in nature by joining small moieties, with each other producing a huge molecule in a good yield. The mind of that reaction is used in biomolecules synthesis, pharmacological and various biometric applications. The first Click reaction is the Copper compounds-catalyzed reaction of an azide with an alkyne (CuAAC), this copper-catalyzed “click” does not require legands on the metal but the metal oxides also can accelerate the reactions. For enhancement the products of Click reactions we were replacing the copper compounds in a classical reaction by the prepared nanocopper compound (NPs). And measure the consumption of starting material. Behind the evolution is the catalytic effect of nanocopper compounding (NPs) on (H2O2). Owing to the huge surface area of nanocopper compound (NPs), it was found that: the (NPs) can speed up decomposition of H2O2, also can accelerate the classical click reaction.
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