营养不良的15个月大的牛多氨菌素中毒

IF 0.8 4区农林科学 Q3 VETERINARY SCIENCES

Pesquisa Veterinaria Brasileira Pub Date : 2022-01-01 DOI:10.1590/1678-5150-pvb-7102

M. Machado, F. Riet-Correa, P. Pedroso, J. T. Macêdo

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引用次数: 0

摘要

摘要:大环内酯是一种广泛应用于家畜体内的杀菌剂。中毒发生在过量和/或营养不良的情况下，发生在幼畜和遗传敏感品种中。我们描述了在营养不良的15个月大的牛中，doramectin中毒，这些牛接受了推荐剂量的1.6倍。动物表现为流涎、共济失调、运动不协调、不愿运动和胸骨平躺。两只动物自行康复;其中一人死亡并被尸检。未观察到肉眼或显微镜下的变化。这项研究表明，如果给营养不良的牛服用高于推荐剂量的多拉菌素，可能会导致中毒，了解病史对于确定诊断至关重要。

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Doramectin intoxication in malnourished 15-month-old cattle

ABSTRACT: Macrocyclic lactones are widely used as endectocides in farm animals. Intoxications occur in situations of overdose and/or malnutrition, in young animals, and in genetically sensitive breeds. We describe the intoxication by doramectin in malnourished 15-month-old cattle that received 1.6 times the recommended dose. The animals presented salivation, ataxia, motor incoordination, reluctance to move, and sternal recumbency. Two animals recovered spontaneously; one died and was necropsied. No gross or microscopic changes were observed. This study suggests that doramectin may cause intoxication when administered to malnourished cattle in doses higher than those recommended and that knowing the history is essential to establish a diagnosis.

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来源期刊

Pesquisa Veterinaria Brasileira 农林科学-兽医学

CiteScore

1.30

自引率

16.70%

发文量

审稿时长

9-18 weeks

期刊介绍： Pesquisa Veterinária Brasileira - Brazilian Journal of Veterinary Research (http://www.pvb.com.br), edited by the Brazilian College of Animal Pathology in partnership with the Brazilian Agricultural Research Organization (Embrapa) and in collaboration with other veterinary scientific associations, publishes original papers on animal diseases and related subjects. Critical review articles should be written in support of original investigation. The editors assume that papers submitted are not being considered for publication in other journals and do not contain material which has already been published. Submitted papers are peer reviewed. The abbreviated title of Pesquisa Veterinária Brasileira is Pesqui. Vet. Bras.