Investigation on hepatitis B surface antigen among exit personnel at Tianjin port of China in 2019

Objective: To investigate the hepatitis B infection situation of exit physical examination personnel at Tianjin port in 2019, so as to provide data support and theoretical guarantee for disease prevention and dynamic monitoring of hepatitis B infection among physical examination population at Tianjin port. Methods: The venous blood samples of exit personnel at Tianjin port in 2019 were collected, and the hepatitis B antigen in the samples were detected by Electrochemiluminescence technology. According to the collected passenger information, combined with the experimental results, a database of entry-exit medical examination personnel was established and the epidemiological characteristics of hepatitis B were analyzed by statistical method. Results: A total of 3469 people were involved in this study, 134 of them were HBsAg positive, the positive rate was 3.90%. From the perspective of gender, the positive rate of male was 5.51% (127/2303) and that of female was 0.60% (7/1166). The difference of HBV infection level between male and female was statistically significant (x 2 = 50.62, P < 0.001). According to the analysis of different occupations, the positive rate of public servants was the highest, up to 69.10% (85/123); the rest were labor service personnel, pilgrims, crew members and overseas students. The difference of hepatitis B infection level among different occupational groups was statistically significant (x 2 = 1451.82, P < 0.001). The data were divided into 4 groups according to their ages. No positive results were found in 0-20 years old people. The positive rate of 21-40 years old group was 3.23% (84/2597). The positive rate of 41-60 years old group was 10.62% (50/471); the positive rate of people older than 60 years old was not detected, and the difference of hepatitis B infection level among different age groups was statistically significant (x 2 <76.16, P <0.001). Conclusions: There are significant differences between the positive detection rate of hepatitis B surface antigen and the gender, age and occupation category of the subjects in the exit population at Tianjin port in 2019. Men, young adults and civil servants are more likely to be infected with hepatitis B. Therefore, we should focus on prevention and monitoring of the key population.