房颤患者covid后期心脏代谢和心理认知特征

Profilakticheskaya Meditsina Pub Date : 2023-01-01 DOI:10.17116/profmed20232604143

A. Starichkova, L. Khidirova, O. Tsygankova, V. Lukinov

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引用次数: 0

摘要

在世界范围内，受COVID-19长期影响的人数正在增加。患者的长期预后仍然知之甚少。目标。研究合并老年房颤(AF)患者的心脏代谢和心理认知特征，这取决于是否存在covid后综合征(PCS)。材料和方法。观察性分析队列研究纳入223例60-74岁房颤合并合并症(冠状动脉疾病、高血压、肥胖、2型糖尿病)患者，分为两组:1组123例无COVID-19患者，2组110例有COVID-19病史并存在PCS的患者。该研究评估了实验室和仪器测试，并进行了一项使用SPMSQ和HADS问卷评估心理认知障碍的一般临床研究。结果和讨论。在COVID-19幸存者中，与1组患者相比，总胆固醇(TC) (p=0.003)、低密度脂蛋白胆固醇(p<0.001)和甘油三酯(p=0.011)的动脉粥样硬化改变更为明显。COVID-19幸存者的舒张压较低(p<0.001)。此外，2组患者的中位脉压(p<0.001)和心率(p<0.001)较高。2组患者升主动脉直径增大(p<0.001)。焦虑抑郁综合征在合并合并症的COVID-19幸存者中更为常见，临床焦虑(24%，p=0.041)和亚临床抑郁(21%，p=0.015)差异有统计学意义。在评估认知功能时，22%的PCS患者存在中度认知障碍(p=0.005)， 2%的PCS患者存在重度认知障碍(p=0.007)。结论。在合并COVID-19后综合征的老年患者中，观察到心理认知障碍和不良心脏代谢变化的高发率，支持对COVID-19幸存者的一般临床状况和心理认知状态进行长期监测的必要性。版权所有©Media Sphera出版集团2023版权所有。

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Cardiometabolic and psychocognitive features of the post-COVID period in patients with atrial fibrillation

The number of people with long-term consequences of COVID-19 is increasing worldwide. The long-term prognosis for patients remains poorly understood. Objective. To study cardiometabolic and psychocognitive features in comorbid elderly patients with atrial fibrillation (AF), de-pending on the presence of post-COVID syndrome (PCS). Material and methods. The observational analytical cohort study included 223 patients with AF and comorbidity (coronary artery disease, hypertension, obesity, type 2 diabetes mellitus) aged 60-74, who were divided into two groups: group 1 included 123 patients without COVID-19 and group 2 included 110 patients with a history of COVID-19 and the presence of PCS. The study evaluated laboratory and instrumental tests, and a general clinical study assessing psychocognitive disorders using the SPMSQ and HADS questionnaires was conducted. Results and discussion. In COVID-19 survivors, compared with patients of group 1, there were more pronounced atherogenic changes in total cholesterol (TC) (p=0.003), low-density lipoprotein cholesterol (p<0.001), and triglycerides (p=0.011). Lower dia-stolic blood pressure was found in COVID-19 survivors (p<0.001). In addition, patients in group 2 had higher median pulse pressure (p<0.001) and heart rate (p<0.001). In group 2 patients, a larger ascending aorta diameter was observed (p<0.001). The anx-iety-depressive syndrome was more common in COVID-19 survivors with comorbidities, and a statistically significant difference was found in clinical anxiety (24%, p=0.041) and subclinical depression (21%, p=0.015). When assessing cognitive function, mod-erate cognitive impairment was detected in 22% (p=0.005) of patients with PCS and severe cognitive impairment in 2% (p=0.007). Conclusion. In comorbid elderly patients with the post-COVID syndrome, a high prevalence of psychocognitive disorders and adverse cardiometabolic changes were observed, supporting the need for long-term monitoring of the general clinical condition and psychocognitive status of COVID-19 survivors.Copyright © 2023, Media Sphera Publishing Group. All rights reserved.

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来源期刊

Profilakticheskaya Meditsina Medicine-Health Policy

CiteScore

0.90

自引率

0.00%

发文量

108

期刊介绍： The journal "Profilakticheskaya meditsina" (The Russian Journal of Preventive Medicine and Public Health) has been published since 1997 and is intended for healthcare professionals and administrators, politicians, and scientists. A wide range of problems appearing on the pages of the journal is determined by its sociopolitical and scientific-and-practical orientations. The journal covers the problems of health promotion, the prevention and treatment of communicable and non-communicable diseases, such as cardiovascular and respiratory diseases, cancers, diabetes, injuries, and violent death. The main sections of the journal: Organization of Public Health Prevention of Communicable and Non-Communicable Diseases, Health Promotion: Policy and Strategy Sociomedical Aspects of Health Formation Medico-Demographic Aspects of Health Formation Prevention of Communicable and Non-Communicable Diseases Risk Factors for Communicable and Non-Communicable Diseases The Health of Children, Adolescents, and Young People Female Health Male Health Nutrition and Health Smoking and Health Alcohol and Health Guidelines for the Specialist Education Programs for Healthcare Specialists and Patients Experience of Regions A Specialist’s Opinion Reviews.