降低四环素溶液的毒性及氧中DBD作用下的分解动力学

Q3 Physics and Astronomy

Plasma Medicine Pub Date : 2019-01-01 DOI:10.1615/plasmamed.2019031459

A. Gushchin, V. Grinevich, E. Kvitkova, R. Chugunov, T. Izvekova, N. Kruchinina, V. Emzhina, N. Ivantsova, V. Rybkin

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引用次数: 0

摘要

研究了氧介质阻挡放电(DBD)对四环素(THC)水溶液分解和产物生成动力学的影响。四氢大麻酚的分解动力学服从一级动力学顺序，分解度达到90%。确定了分解过程的速率常数和能量效率。四氢大麻酚的分解产物为羧酸类、醛类、CO和CO2。以淡水甲壳类动物大水蚤(Daphnia magna Straus)和网状水蛭(Poecillia reticulata Peters)的存活率来测定水的毒性效应。DBD治疗可显著降低溶液的毒性(降低94.8%)。

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Reducing the Toxicity of Tetracycline Solutions and the Kinetics of Decomposition under the Action of DBD in Oxygen

The effects of a dielectric barrier discharge (DBD) in oxygen on the kinetics of the decomposition and of product formation of aqueous solutions of tetracycline (THC) were studied. The kinetics of THC decomposition obeyed the first kinetic order, and the degree of decomposition reached 90%. The rate constants and the energy efficiency of the decomposition process were determined. The decomposition products of THC were carboxylic acids, aldehydes, CO, and CO2. The toxic effect of water was determined by the survival rate of freshwater crustaceans Daphnia magna Straus and fish Poecillia reticulata Peters. Treatment with DBD led to a significant reduction in the toxicity of the solutions (by 94.8%).

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来源期刊

Plasma Medicine Physics and Astronomy-Physics and Astronomy (all)

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Technology has always played an important role in medicine and there are many journals today devoted to medical applications of ionizing radiation, lasers, ultrasound, magnetic resonance and others. Plasma technology is a relative newcomer to the field of medicine. Experimental work conducted at several major universities, research centers and companies around the world over the recent decade demonstrates that plasma can be used in variety of medical applications. It is already widely used surgeries and endoscopic procedures. It has been shown to control properties of cellular and tissue matrices, including biocompatibility of various substrates. Non-thermal plasma has been demonstrated to deactivate dangerous pathogens and to stop bleeding without damaging healthy tissue. It can be used to promote wound healing and to treat cancer. Understanding of various mechanisms by which plasma can interact with living systems, including effects of reactive oxygen species, reactive nitrogen species and charges, has begun to emerge recently. The aim of the Plasma Medicine journal will be to provide a forum where the above topics as well as topics closely related to them can be presented and discussed. Existing journals on plasma science and technology are aimed for audiences with primarily engineering and science background. The field of Plasma Medicine, on the other hand, is highly interdisciplinary. Some of prospective readers and contributors of the Plasma Medicine journal are expected to have background in medicine and biology. Others might be more familiar with plasma science. The goal of the proposed Plasma Medicine journal is to bridge the gap between audiences with such different backgrounds, without sacrificing the quality of the papers be their emphasis on medicine, biology or plasma science and technology.