设计测定梯度和活性吸收钙的方法来评估移植肾脏的功能

IF 0.2 Q4 TRANSPLANTATION

Vestnik Transplantologii i Iskusstvennyh Organov Pub Date : 2014-06-05 DOI:10.15825/1995-1191-2010-1-51-55

I. Yermakova, V. P. Buzulina, I. E. Borodulin, I. A. Pronchenko, Tomilina Na

{"title":"设计测定梯度和活性吸收钙的方法来评估移植肾脏的功能","authors":"I. Yermakova, V. P. Buzulina, I. E. Borodulin, I. A. Pronchenko, Tomilina Na","doi":"10.15825/1995-1191-2010-1-51-55","DOIUrl":null,"url":null,"abstract":"The dependence between minute calcium and sodium excretion from 1 L glomerular fi ltrate (CaE/GFR; NaE/GFR) with NaE/GFR from 0,1 to 9,71 mmol/l GFR was studied in 103 health volunteers. There was received asymptotique curve with r 2 = 0,54; Y = 0,06 [1 – exp (–x/2,34)]. The nomogramm with con fi dence intervals of 95% was built. On the basis of renal physiology it was offered differentiate gradual (to electrochemical gradiate created by sodium reabsorbtion) and active calcium reabsorbtion. It was assumed that gradual calcium reabsorbtion is equel to sodium reabsorbtion and may be estimate by NaE/GFR, CNa/GFR. We considered that active calcium reabsorbtion is normal if the correlation between CaE/GFR and NaE/GFR is inside being decreased if the correlation is higher and increased if the correlation is lower probable intervals. We proposed T-score CaE/GFR as the quantative parameter of active calcium reabsorbtion. It varied in health volunteers from –1,74 to +2,15. The method was applied in 236 recipients of allotransplanted kidney.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"12 1","pages":"51-55"},"PeriodicalIF":0.2000,"publicationDate":"2014-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"РАЗРАБОТКА МЕТОДА ОПРЕДЕЛЕНИЯ ГРАДИЕНТНОЙ И АКТИВНОЙ РЕАБСОРБЦИИ КАЛЬЦИЯ ДЛЯ ОЦЕНКИ ФУНКЦИИ ПЕРЕСАЖЕННОЙ ПОЧКИ\",\"authors\":\"I. Yermakova, V. P. Buzulina, I. E. Borodulin, I. A. Pronchenko, Tomilina Na\",\"doi\":\"10.15825/1995-1191-2010-1-51-55\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The dependence between minute calcium and sodium excretion from 1 L glomerular fi ltrate (CaE/GFR; NaE/GFR) with NaE/GFR from 0,1 to 9,71 mmol/l GFR was studied in 103 health volunteers. There was received asymptotique curve with r 2 = 0,54; Y = 0,06 [1 – exp (–x/2,34)]. The nomogramm with con fi dence intervals of 95% was built. On the basis of renal physiology it was offered differentiate gradual (to electrochemical gradiate created by sodium reabsorbtion) and active calcium reabsorbtion. It was assumed that gradual calcium reabsorbtion is equel to sodium reabsorbtion and may be estimate by NaE/GFR, CNa/GFR. We considered that active calcium reabsorbtion is normal if the correlation between CaE/GFR and NaE/GFR is inside being decreased if the correlation is higher and increased if the correlation is lower probable intervals. We proposed T-score CaE/GFR as the quantative parameter of active calcium reabsorbtion. It varied in health volunteers from –1,74 to +2,15. The method was applied in 236 recipients of allotransplanted kidney.\",\"PeriodicalId\":43091,\"journal\":{\"name\":\"Vestnik Transplantologii i Iskusstvennyh Organov\",\"volume\":\"12 1\",\"pages\":\"51-55\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2014-06-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Vestnik Transplantologii i Iskusstvennyh Organov\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15825/1995-1191-2010-1-51-55\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"TRANSPLANTATION\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vestnik Transplantologii i Iskusstvennyh Organov","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15825/1995-1191-2010-1-51-55","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"TRANSPLANTATION","Score":null,"Total":0}

引用次数: 0

摘要

1 L肾小球滤过物微量钙钠排泄量(CaE/GFR)的相关性研究研究了103名健康志愿者NaE/GFR与NaE/GFR在0.1 ~ 9.71 mmol/l之间的关系。有接收渐近曲线，r 2 = 0,54;Y = 0,06 [1 - exp (- x/2,34)]。建立置信区间为95%的正态图。在肾脏生理学的基础上，提出了渐进式(钠重吸收产生的电化学梯度)和活性钙重吸收的区别。假设钙的逐渐重吸收等于钠的逐渐重吸收，可以通过NaE/GFR, CNa/GFR来估计。我们认为CaE/GFR与NaE/GFR的相关性在区间内为正常，相关性高则降低，相关性低则升高。我们提出T-score CaE/GFR作为活性钙重吸收的定量参数。在健康志愿者中，它从- 1,74到+2,15不等。该方法应用于236例同种异体肾移植受者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

РАЗРАБОТКА МЕТОДА ОПРЕДЕЛЕНИЯ ГРАДИЕНТНОЙ И АКТИВНОЙ РЕАБСОРБЦИИ КАЛЬЦИЯ ДЛЯ ОЦЕНКИ ФУНКЦИИ ПЕРЕСАЖЕННОЙ ПОЧКИ

The dependence between minute calcium and sodium excretion from 1 L glomerular fi ltrate (CaE/GFR; NaE/GFR) with NaE/GFR from 0,1 to 9,71 mmol/l GFR was studied in 103 health volunteers. There was received asymptotique curve with r 2 = 0,54; Y = 0,06 [1 – exp (–x/2,34)]. The nomogramm with con fi dence intervals of 95% was built. On the basis of renal physiology it was offered differentiate gradual (to electrochemical gradiate created by sodium reabsorbtion) and active calcium reabsorbtion. It was assumed that gradual calcium reabsorbtion is equel to sodium reabsorbtion and may be estimate by NaE/GFR, CNa/GFR. We considered that active calcium reabsorbtion is normal if the correlation between CaE/GFR and NaE/GFR is inside being decreased if the correlation is higher and increased if the correlation is lower probable intervals. We proposed T-score CaE/GFR as the quantative parameter of active calcium reabsorbtion. It varied in health volunteers from –1,74 to +2,15. The method was applied in 236 recipients of allotransplanted kidney.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Vestnik Transplantologii i Iskusstvennyh Organov TRANSPLANTATION-

CiteScore

0.70

自引率

50.00%

发文量

审稿时长

12 weeks

期刊介绍： Organ transplantation is one of the most challenging and complex areas of modern medicine, based on a rapid development of innovative technologies in surgery, anesthesiology and intensive care, cardiovascular surgery, immunology, molecular biology, biotechnology, and natural sciences. Regenerative medicine and the development of artificial and bioartificial organs and systems are the key issues for further progress in transplantation. Cardiology, nephrology, hepatology, endocrinology, and many other medical areas constitute the basis of clinical transplantation. Organization and coordination of organ donation present a serious challenge on a state level requiring cooperation and active work of various health authorities. The development of clinical transplantation in Russia has led to the formation of a wide network of transplant centers. Hundreds of hearts, kidneys, livers, lungs, and pancreases transplantations perform annually. Improvement of transplant availability for patients and an increased number of professionals involved in the transplantation process are the contemporary realities in the Russian Federation. Thus, the journal aims to serve as a forum for an exchange of research information, clinical expertise, current trends and the recent developments in the field of transplantation and organ donation.