Н. И. Габриэлян, Е. М. Горская, Н. Ю. Романова, О. М. Цирульникова
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The review presents data on the role of biofilms formation by opportunistic microbes in surgery. It gives in- formation about the microbial structure of biofilms, their architecture and physiology. The attention was payed to significal importance of microbial communities, which form biofilms in surgery. Mechanisms of increased resistance of biofilms bacteria are compared with plankton. The review includes literature data on the process of formation biofilms on intravascular catheters and methods of inhibition and protection. Methods of studing formation and inhibition of biofilms in vitro and in vivo are presented. Different biotechnology methods, based on using antiadhesive, antiseptic, biophysical resources and biomaterials are discussed.
期刊介绍:
Organ transplantation is one of the most challenging and complex areas of modern medicine, based on a rapid development of innovative technologies in surgery, anesthesiology and intensive care, cardiovascular surgery, immunology, molecular biology, biotechnology, and natural sciences. Regenerative medicine and the development of artificial and bioartificial organs and systems are the key issues for further progress in transplantation. Cardiology, nephrology, hepatology, endocrinology, and many other medical areas constitute the basis of clinical transplantation. Organization and coordination of organ donation present a serious challenge on a state level requiring cooperation and active work of various health authorities. The development of clinical transplantation in Russia has led to the formation of a wide network of transplant centers. Hundreds of hearts, kidneys, livers, lungs, and pancreases transplantations perform annually. Improvement of transplant availability for patients and an increased number of professionals involved in the transplantation process are the contemporary realities in the Russian Federation. Thus, the journal aims to serve as a forum for an exchange of research information, clinical expertise, current trends and the recent developments in the field of transplantation and organ donation.