正畸治疗中疼痛感知的双盲随机临床试验

Silvana Rossi, Milton Santamaria Júnior, G. C. Venezian, Carolina Carmo de Menezes, J. E. Souza, S. Vedovello
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引用次数: 0

摘要

正畸运动可引起疼痛症状,特别是在治疗初期。目的比较口香糖和布洛芬在正畸治疗初期疼痛控制的效果。材料与方法采用1∶1的随机盲临床试验,患者年龄≥18岁。样本量的建立考虑了5%的显著性水平和80%的检验能力,因此每组至少有30名志愿者(n=90)。参与者根据性别、年龄、错牙合的严重程度(由牙齿健康成分(DHC)定义的正畸治疗需求指数(IOTN))和拥挤程度(由利特尔不规则指数确定)进行配对。样本随机分为三组:第一组(对照组)安慰剂;第二组口香糖;第三组布洛芬。在正畸矫治器激活后的前24、36和48小时,用视觉模拟量表(VAS)评估疼痛感觉。采用广义线性模型对数据进行时间重复测量分析。结果激活后24、36、48 h各组疼痛治疗效果比较,差异均无统计学意义(p < 0.05)。结论正畸治疗过程中疼痛控制方法的差异无统计学意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A double-blinded randomized clinical trial of pain perception during orthodontic treatment
Abstract Introduction Orthodontic movement can cause painful symptoms, especially in the early stages of treatment. Objective This study aimed to compare the performance of chewing gum and ibuprofen in pain control during the initial period of orthodontic treatment. Material and method A randomized blind clinical trial, with an allocation ratio of 1:1, was developed with patients aged ≥18 years old. The sample size was established considering a significance level of 5% and test power of 80%, resulting in a minimum of 30 volunteers per group (n=90). Participants were paired regarding sex, age, the severity of malocclusion, defined by the Dental Health Component (DHC) of the Index of Orthodontic Treatment Need (IOTN), and crowding, determined by Little’s irregularity index. The sample was randomly allocated to three groups: Group I (control) placebo; Group II chewing gum; and Group III Ibuprofen. Pain perception was evaluated by the Visual Analog Scale (VAS) in the first 24, 36, and 48 hours after activation of the orthodontic appliance. The data were analyzed by generalized linear models for repeated measures in time. Result No statistically significant difference (p>0.05) was observed among the groups for the methods of pain therapy evaluated in 24, 36, and 48 hours post-activation. Conclusion There was no difference among the method used for pain control during the orthodontic treatment.
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