使用现代统计方法来评估干扰素新生儿和母亲健康状况的关系

IF 0.2 Q4 INFECTIOUS DISEASES

Infektsiya i Immunitet Pub Date : 2014-07-01 DOI:10.15789/2220-7619-2011-4-331-340

S. A. Sel’kov, L. I. Koroleva, A. V. Tishkov, V. B. Anikin, N. Khromov-Borisov

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引用次数: 4

摘要

摘要应用现代统计学方法对健康足月新生儿及其健康母亲的ifn水平进行分析。结果表明，健康足月新生儿的IFN水平不同于母亲，其IFN发生率较高，诱导的IFNα/β和IFNγ的产生增强。新生儿及其母亲IFN状态指标之间的统计显著相互作用已被揭示。所获得的数据对于评估系统中母亲-新生儿的非特异性耐药具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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ПРИМЕНЕНИЕ СОВРЕМЕННЫХ СТАТИСТИЧЕСКИХ МЕТОДОВ ДЛЯ ОЦЕНКИ ВЗАИМОСВЯЗИ ИНТЕРФЕРОНОВОГО СТАТУСА ЗДОРОВОГО НОВОРОЖДЕННОГО И ЕГО МАТЕРИ

Abstract. The analysis of the IFN-status of healthy full-term neonatal infants and their healthy mothers with modern statistical methods was conducted. It was established that the IFN status of healthy full-term neonatal infants differs from the same of their mothers with higher occurrence of IFNs and strengthened induced production of IFNα/β and IFNγ. The statistically significant interaction between indicators of the IFN status of newborns and their mothers has been revealed. The obtained data is important for assessment of nonspecific resistance in system mother–newborn.

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来源期刊

Infektsiya i Immunitet INFECTIOUS DISEASES-

CiteScore

1.40

自引率

50.00%

发文量

审稿时长

10 weeks

期刊介绍： Journal "Infektsiya i immunitet" ("Russian Journal of Infection and Immunity") established by Northwest Branch of RAMS, St. Petersburg Pasteur Institute and the St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists, with the participation of the St. Petersburg branch of All-Russian Practical Society of epidemiologists, microbiologists and parasitologists at St. Petersburg and Leningrad region. The journal is devoted to numerous aspects of the interaction between different microorganisms and the host organism. Journal is of interest for microbiologists, immunologists, epidemiologists and clinicians. The most detailed discussion of the following questions: • molecular basis of infections caused by pathogenic bacteria, fungi and parasites; • mechanisms of pathogenicity of microorganisms; • the impact of microbial virulence factors on host cells; • factors and mechanism to protect the host from infection; • factors of nonspecific and specific immunity; • experimental models of infectious disease; • development of vaccines and nonspecific anti-infectious defense.