Fatal Outcome of Alimentar Escherichia Coli O157: H7 Toxiinfection

Medical records showed that in two young tourists, different gender from Macedonia developed at the same time symptoms of acute alimentary toxiinfection. In male person, there was regression of symptoms after completion of home treatment (oral rehydratation and diet). In the female case (18 years) home treatment conducted under the same conditions, did not yield satisfactory results. Disease progression was monitored clinically from the appearance of sub febrile temperature, with vomiting, watery diarrhea and abdominal pain to development of hemorrhagic colitis (spasmodic pain in the lower abdomen, then bloody diarrhea), which forced her to search medical help. The dramatic course of the development of clinical disease, occur 7- 8 days after onset. Coincides with the early development of hemolytic uremic syndrome (HUS), and later development of acute renal failure. Those 18-th days from the onset of the disease ended in death. In the last stage of hospital treatment and analyzing, at the Nephrology Clinic in Skopje, swab of the mucous membrane proved verotoxin of E. coli O157.