确定剂量分布在肺模拟器对象与蒙特卡罗模拟使用代码Penelope

Pub Date : 2019-12-01 DOI:10.15446/MO.N59.75714
Danny G. Apaza, Ruben D. Chahuara, Pedro P. Sellerico, J. L. Vega
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引用次数: 1

摘要

放射治疗是用于癌症患者的一种治疗方法,其中肿瘤的体积被照射,考虑到各种标准,以避免损害健康组织,因此,重要的是要确定给予的剂量是正确的。为了建立一种精确的方法来验证治疗计划,以环氧树脂、酚醛球和碳酸钙为基础构建了肺和软组织模拟器。这些数据通过电子扫描显微镜进行分析,并使用PENELOPE v.2008代码通过蒙特卡罗模拟进行验证,并与美国国家标准与技术研究所(NIST)的出版物进行比较。在此基础上,构建并模拟了辐射与均匀模拟器(肺)和非均匀模拟器(肺、软组织、肺)的相互作用。本工作的主要目的是利用模拟物体在类似于放射治疗中临床病例照射的条件下,获得1x1 cm2和2x2 cm2小场的剂量深度曲线(PDP),光子束能量为6兆电子伏特。
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DETERMINATION OF DOSE DISTRIBUTION ON LUNG SIMULATOR OBJECT WITH MONTE CARLO SIMULATION USING CODE PENELOPE
Radiotherapy is one of the treatments used in patients suffering from cancer, where the volume of the tumor is irradiated, considering various criteria to avoid damaging healthy tissues, therefore it is important to be certain that the dose given is correct. In order to develop a precise method of verification of treatment planning, simulators of lung and soft tissue were constructed based on epoxy resin, phenolitic spheres and calcium carbonate. These were analyzed by electronic scanning microscopy and validated by Monte Carlo simulation using PENELOPE v.2008 code compared to publications from the National Institute of Standards and Technology (NIST). With this, the interaction of the radiation with homogeneous simulators (lung) and heterogeneous (lung, soft tissue, lung) constructed and simulated was evaluated. The main objective of this work is the use of simulating objects in conditions similar to that used in the irradiation of a clinical case in radiotherapy, obtaining dose depth curves (PDP) for small field of 1x1 cm2 and 2x2 cm 2, with photon beams of 6 MeV energy.
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