Yury Gennadievich Baranovsky, E. Y. Shapovalova, Tatiana Boyko, I. A. Lugin, S. V. Harchenko, A. Baranovsky, A. Kubyshkin
{"title":"同种异体真皮成纤维细胞移植海绵内小鼠缺血性皮肤创面t淋巴细胞及形态学变化","authors":"Yury Gennadievich Baranovsky, E. Y. Shapovalova, Tatiana Boyko, I. A. Lugin, S. V. Harchenko, A. Baranovsky, A. Kubyshkin","doi":"10.14300/mnnc.2023.18037","DOIUrl":null,"url":null,"abstract":"The problem of healing long-term skin defects, complicated by venous insufficiency, remains a problem despite many known treatments. The article researches immunological compatibility and efficiency of the use of collagen sponges with skin allogeneic fibroblasts for stimulation of wound healing. Sixteen mature C57/B1 mice were divided into two equal groups: control and experimental. In the 10th-day dynamic, the stimulation method was found to be highly effective by associating the collagen sponge with the allofibroblasts, which allows a significant improvement in the morphological characteristics of the sample biopsy and does not cause an autoimmune response to the transplant","PeriodicalId":53493,"journal":{"name":"Medical News of North Caucasus","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"T-lymphocytes and morphology of ischemic cutaneous wound of mice within collagen sponge with allogenic dermal fibroblasts transplantation\",\"authors\":\"Yury Gennadievich Baranovsky, E. Y. Shapovalova, Tatiana Boyko, I. A. Lugin, S. V. Harchenko, A. Baranovsky, A. Kubyshkin\",\"doi\":\"10.14300/mnnc.2023.18037\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The problem of healing long-term skin defects, complicated by venous insufficiency, remains a problem despite many known treatments. The article researches immunological compatibility and efficiency of the use of collagen sponges with skin allogeneic fibroblasts for stimulation of wound healing. Sixteen mature C57/B1 mice were divided into two equal groups: control and experimental. In the 10th-day dynamic, the stimulation method was found to be highly effective by associating the collagen sponge with the allofibroblasts, which allows a significant improvement in the morphological characteristics of the sample biopsy and does not cause an autoimmune response to the transplant\",\"PeriodicalId\":53493,\"journal\":{\"name\":\"Medical News of North Caucasus\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical News of North Caucasus\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14300/mnnc.2023.18037\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical News of North Caucasus","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14300/mnnc.2023.18037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
T-lymphocytes and morphology of ischemic cutaneous wound of mice within collagen sponge with allogenic dermal fibroblasts transplantation
The problem of healing long-term skin defects, complicated by venous insufficiency, remains a problem despite many known treatments. The article researches immunological compatibility and efficiency of the use of collagen sponges with skin allogeneic fibroblasts for stimulation of wound healing. Sixteen mature C57/B1 mice were divided into two equal groups: control and experimental. In the 10th-day dynamic, the stimulation method was found to be highly effective by associating the collagen sponge with the allofibroblasts, which allows a significant improvement in the morphological characteristics of the sample biopsy and does not cause an autoimmune response to the transplant
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