粉红丝带带给我们的教训

J. Abraham
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The initial focus was on screening for breast cancer and early detection of disease, and it has now evolved into a platform to “promote a national dialogue on breast cancer.” The story of the pink ribbon as the symbol of breast cancer is also interesting. Evelyn Lauder, an executive at Estee Lauder Inc, started the Breast Cancer Research Foundation in 1993 and together with a friend selected the pink ribbon as the foundation’s symbol. But even before that, in 1991, the Susan G. Komen Foundation had given the pink ribbon to participants in a race in New York City for breast cancer survivors. Breast cancer awareness month is now a global event. The plea for greater awareness of breast cancer, more research and the quest for a cure reached the White House in October 2012, when President Obama said in a proclamation, “This month, we stand with the mothers, daughters, sisters, aunts, and friends who have been affected by breast cancer, and we recognize the ongoing efforts of dedicated advocates, researchers, and health care providers who strive each day to defeat this terrible disease. In memory of the loved ones we have lost and inspired by the resilience of those living with the disease, let us strengthen our resolve to lead our Nation toward a future free from cancer in all its forms. 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As a result of this strong advocacy, breast cancer researchers received about $602.7 million funding from the National Cancer Institute in 2012, whereas prostate cancer researchers received about $265.1 million and lung cancer researchers, $314.6 million. There’s no disputing the fact that there is a huge difference in funding between breast cancer and other cancers. But because of that increased funding, we have a better understanding of the intricacies of breast cancer biology, the heterogeneity of the disease, and its genomic classification. Over the past 10 years that newly acquired knowledge has helped scientists develop therapies that are more targeted and that allow clinicians to prescribe more personalized and highly effective medicines for their breast cancer patients. These advances have improved patient quality of life, decreased the therapies’ side effects, and decreased mortality. 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引用次数: 0

摘要

“我厌倦了你的粉红丝带!”我的一位白血病医生在一次会议上半开玩笑地说。他并不孤单。一些人认为,把十月作为乳腺癌宣传月的宣传太多了。如果有一种颜色,一种疾病,一个月被公众清楚地铭记,那就是粉红丝带和十月份的乳腺癌意识。从杂货店到国家橄榄球联盟(National Football League)的球队,在那个月宣传乳腺癌意识的信息占据了优先地位。谈论一种疾病是不是太多了?我们是否将这一信息商业化,可能会偏离预期的目的?全国乳腺癌宣传月始于1985年,由美国癌症协会和阿斯利康(当时被称为帝国化学工业)合作发起。最初的重点是筛查乳腺癌和早期发现疾病,现在已经发展成为一个“促进全国乳腺癌对话”的平台。粉红色丝带作为乳腺癌的象征的故事也很有趣。雅诗兰黛公司(Estee Lauder Inc .)的高管伊芙琳·兰黛(Evelyn Lauder)于1993年创办了乳腺癌研究基金会(Breast Cancer Research Foundation),并与一位朋友一起选择粉色丝带作为基金会的标志。但在此之前,1991年,苏珊·g·科曼基金会(Susan G. Komen Foundation)曾在纽约市为乳腺癌幸存者举办的一场比赛中,为参赛者颁发了粉色丝带。乳腺癌宣传月现在是一个全球性的活动。2012年10月,人们呼吁提高对乳腺癌的认识,进行更多的研究,并寻求治疗方法,奥巴马总统在一份声明中说:“这个月,我们与受乳腺癌影响的母亲、女儿、姐妹、阿姨和朋友们站在一起,我们认识到致力于倡导者、研究人员和卫生保健提供者每天努力战胜这种可怕疾病的持续努力。”为了纪念我们失去的亲人,并受到癌症患者顽强精神的鼓舞,让我们坚定决心,领导我们的国家走向一个没有一切形式癌症的未来。我鼓励公民、政府机构、私营企业、非营利组织和所有其他感兴趣的团体参加活动,提高人们对美国人可以做些什么来预防乳腺癌的认识。”我不否认粉红丝带在10月份被过度曝光,但作为一名照顾患有这种毁灭性疾病的年轻和老年乳腺癌患者的乳腺癌医生,我怎么能告诉全世界130万女性,包括美国的232340名女性,她们将在2013年被诊断患有乳腺癌,她们在10月份受到了过度的关注?我该如何向今年死于乳腺癌的全球50万女性(其中39620人在美国)中的幸存者解释这一点呢?我怎样才能告诉那些母亲、姐妹和女儿们,她们受到了太多的关注?由于这种强有力的倡导,乳腺癌研究人员在2012年从美国国家癌症研究所(National cancer Institute)获得了约6.027亿美元的资助,而前列腺癌研究人员获得了约2.651亿美元,肺癌研究人员获得了3.146亿美元。毫无疑问,乳腺癌和其他癌症的治疗经费存在巨大差异。但是由于资金的增加,我们对乳腺癌生物学的复杂性,疾病的异质性,以及它的基因组分类有了更好的了解。在过去的10年里,新获得的知识帮助科学家开发出更有针对性的治疗方法,使临床医生能够为乳腺癌患者开出更个性化、更有效的药物。这些进步提高了患者的生活质量,减少了治疗的副作用,降低了死亡率。common Oncol 2013;10:277-278©2013 Frontline Medical Communications DOI: 10.12788/j.cmonc.0067来自编辑
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lessons from the pink ribbon
“I am tired of your pink ribbons!” one of my leukemia doctors said half jokingly in a meeting. He is not alone. Some people think there is too much hype about October as the breast cancer awareness month. If there is one color, one disease, and one month that is clearly etched in public memory, is the pink ribbon and breast cancer awareness during the month of October. From grocery stores to National Football League teams, the message of breast cancer awareness during that month takes precedence. Is it too much to talk about one disease? Are we commercializing this message and perhaps detracting from the intended purpose? National breast cancer awareness month was started in 1985 by a partnership between American Cancer Society and AstraZeneca (then known as Imperial Chemical Industries). The initial focus was on screening for breast cancer and early detection of disease, and it has now evolved into a platform to “promote a national dialogue on breast cancer.” The story of the pink ribbon as the symbol of breast cancer is also interesting. Evelyn Lauder, an executive at Estee Lauder Inc, started the Breast Cancer Research Foundation in 1993 and together with a friend selected the pink ribbon as the foundation’s symbol. But even before that, in 1991, the Susan G. Komen Foundation had given the pink ribbon to participants in a race in New York City for breast cancer survivors. Breast cancer awareness month is now a global event. The plea for greater awareness of breast cancer, more research and the quest for a cure reached the White House in October 2012, when President Obama said in a proclamation, “This month, we stand with the mothers, daughters, sisters, aunts, and friends who have been affected by breast cancer, and we recognize the ongoing efforts of dedicated advocates, researchers, and health care providers who strive each day to defeat this terrible disease. In memory of the loved ones we have lost and inspired by the resilience of those living with the disease, let us strengthen our resolve to lead our Nation toward a future free from cancer in all its forms. I encourage citizens, government agencies, private businesses, nonprofit organizations, and all other interested groups to join in activities that will increase awareness of what Americans can do to prevent breast cancer.” I don’t dispute that the pink ribbon gets excessive exposure during the month October, but as a breast cancer doctor who cares for young and elderly patients with this devastating illness, how can I tell the 1.3 million women around the world, including the 232,340 women in the United States, who will be diagnosed in 2013 with breast cancer that they are getting undue attention during October? How can I explain this to the survivors of the half a million women worldwide (39,620 of those in the United States) who succumbed to the disease this year? How we can I tell those mothers, sisters, and daughters that they are getting too much attention? As a result of this strong advocacy, breast cancer researchers received about $602.7 million funding from the National Cancer Institute in 2012, whereas prostate cancer researchers received about $265.1 million and lung cancer researchers, $314.6 million. There’s no disputing the fact that there is a huge difference in funding between breast cancer and other cancers. But because of that increased funding, we have a better understanding of the intricacies of breast cancer biology, the heterogeneity of the disease, and its genomic classification. Over the past 10 years that newly acquired knowledge has helped scientists develop therapies that are more targeted and that allow clinicians to prescribe more personalized and highly effective medicines for their breast cancer patients. These advances have improved patient quality of life, decreased the therapies’ side effects, and decreased mortality. Commun Oncol 2013;10:277-278 © 2013 Frontline Medical Communications DOI: 10.12788/j.cmonc.0067 From the Editor
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