使用体外DIN胃肠模型评估马来西亚Lynas稀土加工厂废物中铅的健康风险和生物可及性

IF 0.5 Q4 ENGINEERING, ENVIRONMENTAL
Y. M. I. Perama, M. Hussin, S. M. Fadzil, K. K. Siong
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引用次数: 0

摘要

本研究采用体外DIN消化模型研究了马来西亚莱纳斯稀土加工厂收集的水浸净化(WLP)废物中铅的生物可及性。研究结果得出污染因子(Cf)为2.7,认为WLP废弃物中存在中等水平的铅污染。在5小时的研究期间,胃和胃肠期消化的WLP废物中Pb的生物可及性分别为0.064±0.010 ~ 0.080±0.010%和0.018±0.013 ~ 0.103±0.046%。为评价WLP废弃物中Pb的人体健康风险,计算了生物可及性估计日摄入量(BEDI)和生物可及性目标危害商(BTHQ)。与成人的数值相比,儿童的数值超过了建议的安全限值,表明存在潜在的人体健康风险。本研究结果表明,应进一步评价和监测Lynas废物处理设施的WLP废物,以消除与人类意外接触铅有关的任何不利健康影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Health risk and bioaccessibility assessment of lead in waste from the Malaysian Lynas rare earth processing plant using an in vitro DIN gastrointestinal model
This study examines the bioaccessibility of lead from water leach purification (WLP) waste collected from the Malaysian Lynas rare earth processing plant using an in vitro DIN digestion model. A contamination factor (Cf) value of 2.7 was obtained from study results, which is considered to be a moderate level of Pb contamination in WLP waste. The bioaccessibility of Pb in digested WLP waste ranged between 0.064 ± 0.010 to 0.080 ± 0.010% and 0.018 ± 0.013 to 0.103 ± 0.046% in the gastric and gastrointestinal phases f, respectively, during the 5-hour study period. To evaluate the human health risks associated with Pb in WLP waste, the bioaccessible estimated daily intake (BEDI) and bioaccessible target hazard quotient (BTHQ) were calculated. The values obtained for children exceeded the recommended safe limit, in contrast to the values obtained for adults, indicating potential human health risks. The results of this study suggest that the WLP waste from Lynas waste disposal facility should be further evaluated and monitored to eliminate any adverse health effects associated with accidental human exposure to Pb.
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来源期刊
CiteScore
1.00
自引率
0.00%
发文量
66
期刊介绍: IJETM is a refereed and authoritative source of information in the field of environmental technology and management. Together with its sister publications IJEP and IJGEnvI, it provides a comprehensive coverage of environmental issues. It deals with the shorter-term, covering both engineering/technical and management solutions.
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