非编码RNA本体的发展

Pub Date : 2016-01-01 DOI:10.1504/IJDMB.2016.077072

Jingshan Huang, K. Eilbeck, Barry Smith, J. Blake, D. Dou, Weili Huang, D. Natale, A. Ruttenberg, Jun Huan, Michael T. Zimmermann, Guoqian Jiang, Yu Lin, Bin Wu, Harrison J. Strachan, Nisansa de Silva, M. V. Kasukurthi, V. Jha, Y. He, Shaojie Zhang, Xiaowei Wang, Zixing Liu, G. Borchert, M. Tan

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引用次数: 11

摘要

在过去的十年中，非编码rna (ncRNAs)的鉴定有了显著的改进。另一方面，由于缺乏一个全面的本体作为该领域的通用数据元素和数据交换标准，ncRNA数据的语义标注面临着严峻的挑战。我们开发了非编码RNA本体(NCRO)来处理这种情况。通过提供正式定义的ncRNA控制词汇表，NCRO旨在填补大量ncRNA生物学和临床数据的语义注释中特定且急需的空缺。

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The development of non-coding RNA ontology

Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data elements and data exchange standards in the field. We developed the Non-Coding RNA Ontology (NCRO) to handle this situation. By providing a formally defined ncRNA controlled vocabulary, the NCRO aims to fill a specific and highly needed niche in semantic annotation of large amounts of ncRNA biological and clinical data.

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