低剂量辐照水蚤的特殊效应及寿命

Q4 Medicine

International Journal of Low Radiation Pub Date : 2011-06-13 DOI:10.1504/IJLR.2011.040647

I. B. Bychkovskaya, E. Sarapultseva

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引用次数: 4

摘要

研究了低辐射剂量对特定物种的非特异性影响。这些效应与随机效应根本不同。它们在低剂量下具有质量特征和完整的外观。所研究的效应类型的特征表现是细胞死亡概率的稳步增加。早期对大水蚤的模型实验表明，低剂量(0.1、1和20 Gy, LD 50/30 = 100 Gy)所研究的损伤类型可以导致水蚤死亡率的剂量无关性增加。目前的研究表明，所研究的这种效应在最低0.1 Gy的剂量下可导致水蚤的预期寿命缩短。由于所研究的影响是在生物体水平上观察到的，因此假定即使在相对较低剂量的辐射下，它也可能影响哺乳动物(包括人类)的预期寿命。

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Special effects of low doses and lifespan of irradiated daphnids

Specific species-unspecific effects of low-radiation doses were studied. These effects are fundamentally different from stochastic effects. They have a mass character and full appearance at low doses for the species. The characteristic manifestation of the studied type of effect is a steady increase in the probability of cell death. Earlier in the model experiments on the crustacean Daphnia magna it was shown that the studied type of damage at low doses (0.1, 1 and 20 Gy, LD 50/30 = 100 Gy) can develop a dose-independent increased mortality of irradiated daphnids. The present study shows that the studied type of effect can lead to reduced life expectancy of daphnids at a lowest dose of 0.1 Gy. Owing to the fact that the studied effect is observed at organism level, it is assumed that it could affect the life expectancy in mammals (including humans) even at relatively low doses of radiation.

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来源期刊

International Journal of Low Radiation Environmental Science-Health, Toxicology and Mutagenesis

自引率

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发文量

期刊介绍： The IJLR is a peer-reviewed journal dedicated to the publication of research articles, review papers and technical notes in all domains related to low-dose radiation, among which are the biological and health effects in humans and the biota, in vitro and in vivo research on low radiation effects, regulatory and policy aspects, risk estimation and public perception.