COVID - 19患者的超声心动图表现和临床特征

Q4 Medicine
H. Wang, Q. Deng, Y. Zhang, W. Hu, Y. Cheng, X. Zhou, J. Yan, H. Ping, B. Hu
{"title":"COVID - 19患者的超声心动图表现和临床特征","authors":"H. Wang, Q. Deng, Y. Zhang, W. Hu, Y. Cheng, X. Zhou, J. Yan, H. Ping, B. Hu","doi":"10.14188/j.1671-8852.2020.0605","DOIUrl":null,"url":null,"abstract":"Objective: To analyze the echocardiographic manifestations and clinical features of 98 patients with COVID‑19, and to explore whether there is potential myocardial injury in COVID‑19 patients. Methods: Patients diagnosed with COVID‑19 in Renmin Hospital of Wuhan University were retrospectively investigated. Echocardiography was performed on all the patients. Diameters of chamber, thickness of ventricular wall were measured routinely to explore whether there were structural changes, while left ventricular ejection fraction (LVEF) and tricuspid annular plane systolic excursion (TAPSE) were assessed for function evaluation. Signs of pericardial effusion and pulmonary hypertension were also focused on in our study. At the same time, clinical data related to the myocardial injury was collected, including Troponin I (cTnI), creatine kinase‑MB (CKMB), and N‑terminal pro‑brain natriuretic peptide (NT‑pro BNP). Patients were divided into the severe group and the non‑severe group, and the differences of ultrasound results and clinical data between the two groups were analyzed. Results: No typical echocardiographic signs of viral myocarditis were observed in our study, such as ventricular enlargement, thickening of the ventricular wall and cardiac dysfunction. Positive findings in echocardiography observed mainly included signs of pericardial effusion and pulmonary hypertension. By comparing the clinical data of the two groups, the age of the severe group was significantly older (median age 66.0 years [IQR: 56.0‑77.0] vs 59.0 years [IQR: 42.0‑69.0], P=0.02), and the levels of CRP, procalcitonin and D‑Dimer were significantly increased in the severe group. Conclusion: Although the echocardiography of patients with COVID‑19 had no typical manifestations, the level of myocardial markers was significantly increased in severe patients, suggesting the potential myocardial injury. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.","PeriodicalId":35402,"journal":{"name":"武汉大学学报(医学版)","volume":"42 1","pages":"872-877"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Echocardiographic findings and clinical features of COVID‑19 patients\",\"authors\":\"H. Wang, Q. Deng, Y. Zhang, W. Hu, Y. Cheng, X. Zhou, J. Yan, H. Ping, B. Hu\",\"doi\":\"10.14188/j.1671-8852.2020.0605\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To analyze the echocardiographic manifestations and clinical features of 98 patients with COVID‑19, and to explore whether there is potential myocardial injury in COVID‑19 patients. Methods: Patients diagnosed with COVID‑19 in Renmin Hospital of Wuhan University were retrospectively investigated. Echocardiography was performed on all the patients. Diameters of chamber, thickness of ventricular wall were measured routinely to explore whether there were structural changes, while left ventricular ejection fraction (LVEF) and tricuspid annular plane systolic excursion (TAPSE) were assessed for function evaluation. Signs of pericardial effusion and pulmonary hypertension were also focused on in our study. At the same time, clinical data related to the myocardial injury was collected, including Troponin I (cTnI), creatine kinase‑MB (CKMB), and N‑terminal pro‑brain natriuretic peptide (NT‑pro BNP). Patients were divided into the severe group and the non‑severe group, and the differences of ultrasound results and clinical data between the two groups were analyzed. Results: No typical echocardiographic signs of viral myocarditis were observed in our study, such as ventricular enlargement, thickening of the ventricular wall and cardiac dysfunction. Positive findings in echocardiography observed mainly included signs of pericardial effusion and pulmonary hypertension. By comparing the clinical data of the two groups, the age of the severe group was significantly older (median age 66.0 years [IQR: 56.0‑77.0] vs 59.0 years [IQR: 42.0‑69.0], P=0.02), and the levels of CRP, procalcitonin and D‑Dimer were significantly increased in the severe group. Conclusion: Although the echocardiography of patients with COVID‑19 had no typical manifestations, the level of myocardial markers was significantly increased in severe patients, suggesting the potential myocardial injury. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.\",\"PeriodicalId\":35402,\"journal\":{\"name\":\"武汉大学学报(医学版)\",\"volume\":\"42 1\",\"pages\":\"872-877\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"武汉大学学报(医学版)\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.14188/j.1671-8852.2020.0605\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"武汉大学学报(医学版)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.14188/j.1671-8852.2020.0605","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

目的:分析98例COVID - 19患者的超声心动图表现及临床特征,探讨COVID - 19患者是否存在潜在的心肌损伤。方法:对武汉大学人民医院诊断为COVID - 19的患者进行回顾性调查。所有患者均行超声心动图检查。常规测量室径、室壁厚度,观察是否有结构改变,评估左室射血分数(LVEF)和三尖瓣环平面收缩偏移(TAPSE),评价功能。心包积液和肺动脉高压的征象也是我们研究的重点。同时收集与心肌损伤相关的临床资料,包括肌钙蛋白I (cTnI)、肌酸激酶MB (CKMB)、N端脑利钠肽前体(NT - pro BNP)。将患者分为重症组和非重症组,分析两组超声检查结果及临床资料的差异。结果:本研究未见病毒性心肌炎的典型超声心动图征象,如心室增大、室壁增厚和心功能障碍。超声心动图阳性表现主要包括心包积液和肺动脉高压。对比两组临床资料,重症组患者年龄明显偏大(中位年龄66.0岁[IQR: 56.0 ~ 77.0] vs中位年龄59.0岁[IQR: 42.0 ~ 69.0], P=0.02),且重症组CRP、降钙素原、D -二聚体水平明显升高。结论:虽然COVID - 19患者超声心动图无典型表现,但重症患者心肌标志物水平明显升高,提示可能存在心肌损伤。©2021,武汉大学医学杂志编辑委员会。版权所有。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Echocardiographic findings and clinical features of COVID‑19 patients
Objective: To analyze the echocardiographic manifestations and clinical features of 98 patients with COVID‑19, and to explore whether there is potential myocardial injury in COVID‑19 patients. Methods: Patients diagnosed with COVID‑19 in Renmin Hospital of Wuhan University were retrospectively investigated. Echocardiography was performed on all the patients. Diameters of chamber, thickness of ventricular wall were measured routinely to explore whether there were structural changes, while left ventricular ejection fraction (LVEF) and tricuspid annular plane systolic excursion (TAPSE) were assessed for function evaluation. Signs of pericardial effusion and pulmonary hypertension were also focused on in our study. At the same time, clinical data related to the myocardial injury was collected, including Troponin I (cTnI), creatine kinase‑MB (CKMB), and N‑terminal pro‑brain natriuretic peptide (NT‑pro BNP). Patients were divided into the severe group and the non‑severe group, and the differences of ultrasound results and clinical data between the two groups were analyzed. Results: No typical echocardiographic signs of viral myocarditis were observed in our study, such as ventricular enlargement, thickening of the ventricular wall and cardiac dysfunction. Positive findings in echocardiography observed mainly included signs of pericardial effusion and pulmonary hypertension. By comparing the clinical data of the two groups, the age of the severe group was significantly older (median age 66.0 years [IQR: 56.0‑77.0] vs 59.0 years [IQR: 42.0‑69.0], P=0.02), and the levels of CRP, procalcitonin and D‑Dimer were significantly increased in the severe group. Conclusion: Although the echocardiography of patients with COVID‑19 had no typical manifestations, the level of myocardial markers was significantly increased in severe patients, suggesting the potential myocardial injury. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
武汉大学学报(医学版)
武汉大学学报(医学版) Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
7289
期刊介绍:
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信