{"title":"囊性纤维化。","authors":"U. Stephan, M. Götz, K. Stephan, S. Bender","doi":"10.1378/chest.114.4_supplement.333s","DOIUrl":null,"url":null,"abstract":"Cystic fibrosis (CF) is a fatal, inherited disease found in humans [4] and characterized by buildup of thick, sticky mucus, particularly in the respiratory and digestive tracts. The abnormally thick mucus prevents the pancreas from functioning normally; it often leads to digestive problems and chronic lung infections. Cystic fibrosis is most prevalent in Caucasian individuals, and approximately 1 in every 29 individuals in the US is a carrier for the mutated CF gene. There are an estimated 30,000 reported cystic fibrosis [5] cases in the US, and 70,000 reported cases worldwide, although the international number is undoubtedly low due to underreporting or early deaths.","PeriodicalId":75829,"journal":{"name":"Ergebnisse der inneren Medizin und Kinderheilkunde","volume":"44 1","pages":"76-174"},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1378/chest.114.4_supplement.333s","citationCount":"0","resultStr":"{\"title\":\"Cystic fibrosis.\",\"authors\":\"U. Stephan, M. Götz, K. Stephan, S. Bender\",\"doi\":\"10.1378/chest.114.4_supplement.333s\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cystic fibrosis (CF) is a fatal, inherited disease found in humans [4] and characterized by buildup of thick, sticky mucus, particularly in the respiratory and digestive tracts. The abnormally thick mucus prevents the pancreas from functioning normally; it often leads to digestive problems and chronic lung infections. Cystic fibrosis is most prevalent in Caucasian individuals, and approximately 1 in every 29 individuals in the US is a carrier for the mutated CF gene. There are an estimated 30,000 reported cystic fibrosis [5] cases in the US, and 70,000 reported cases worldwide, although the international number is undoubtedly low due to underreporting or early deaths.\",\"PeriodicalId\":75829,\"journal\":{\"name\":\"Ergebnisse der inneren Medizin und Kinderheilkunde\",\"volume\":\"44 1\",\"pages\":\"76-174\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1378/chest.114.4_supplement.333s\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ergebnisse der inneren Medizin und Kinderheilkunde\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1378/chest.114.4_supplement.333s\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ergebnisse der inneren Medizin und Kinderheilkunde","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1378/chest.114.4_supplement.333s","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Cystic fibrosis (CF) is a fatal, inherited disease found in humans [4] and characterized by buildup of thick, sticky mucus, particularly in the respiratory and digestive tracts. The abnormally thick mucus prevents the pancreas from functioning normally; it often leads to digestive problems and chronic lung infections. Cystic fibrosis is most prevalent in Caucasian individuals, and approximately 1 in every 29 individuals in the US is a carrier for the mutated CF gene. There are an estimated 30,000 reported cystic fibrosis [5] cases in the US, and 70,000 reported cases worldwide, although the international number is undoubtedly low due to underreporting or early deaths.