Comparison of Lornoxicam and Diclofenac Injections for Post Day Case Laparoscopic Cholecystectomy Pain Relief : A Prospective, Randomized, Single-Blind, Controlled Study

Background: The aim of the study was to compare and evaluate the efficacy and safety of Lornoxicam and Diclofenac injections in the management of postlaparoscopic cholecystectomy pain. Methods: Sixty patients were enrolled in the study. The patients were randomly allocated to one of three groups (20 patients in each): Diclofenac (D, received 75 mg of diclofenac ______________________________ Corresponding author Gamal Abdalla Mohamed Ejaimi Tel: +966558037840 Email: gamalejaimi@hotmail.com I.M.), Lornoxicam (L, received 16 mg of lornoxicam intravenously), and Controlled (C, received 5 ml of normal saline intravenously). Drugs were injected at the time of trocar‘s holes closure. Systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), respiratory rate (RR), oxygen saturation and pain score were recorded as a baseline and every 20 minutes post-operatively. The need for postoperative rescue analgesia was assessed per 0–10. Numerical Pain Scale at 0, 20, 40 and 60 minutes. Rescue analgesia was provided when patients had developed mild pain.