全膝关节置换术后感染调查和治疗失败,导致膝上截肢

Sandra Patton
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摘要

索赔人于2007年11月因骨关节炎接受了左侧全膝关节置换术。他之前就有一些健康问题,包括二型糖尿病、牛皮癣和憩室炎。他之前成功地接受了右膝置换术。手术无并发症,但在三到四天内,伤口开始出血并裂开,2007年12月13日,他去了急诊室。伤口又红又痛。采集了棉签并给予氟氯西林。没有指示他打电话询问结果。实验室报告B群链球菌对氟氯西林敏感,但剂量非常大,建议改用阿莫西林。他没有被告知结果,抗生素也没有改变。他的病情继续恶化,2007年12月22日,他被当作急诊收治。他于2007年12月22日接受了开放性清创、冲洗和换药,并确认感染“与以前一样”,并且在他的血液中也存在感染,因此他患有B群链球菌败血症。医院的卫生标准很差,窗台上放着脏的敷料,脏床单上铺着干净的床单,空的洗手液瓶子。出院后复查,决定取出植入物,患者于2008年2月1日进行了一期翻修手术。组织样品中生长有凝固酶阴性葡萄球菌,未见B组链球菌。静脉注射万古霉素两周,口服利奈唑胺三周。索赔人出院时腿部装有夹板,在他的家中严重残疾,这是一栋维多利亚式的四层连栋房屋,楼上有一个浴室。他实际上被限制在楼下的两个房间里。他于2008年5月23日接受了第二期翻修手术,围手术期给予预防性头孢呋辛,但术中未采集样本进行显微镜和培养。2008年5月27日采集的伤口拭子中生长凝固酶阴性葡萄球菌,与一期翻修手术时发现的细菌相同,但没有进一步静脉注射抗生素。索赔人于2008年5月26日出院,伤口仍在渗出;它继续出院,他于2008年5月29日再次入院。伤口拭子
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Failure to investigate and treat infection after total knee replacement, leading to above-knee amputation
The claimant underwent left total knee replacement surgery for osteoarthritis in November 2007. He had a number of pre-existing health problems, including type II diabetes, psoriasis and diverticulitis. He had previously undergone a successful replacement of his right knee. Surgery proceeded without complication, but within three to four days the wound began to bleed, opened up, and on 13 December 2007,he attended A&E. The wound was red and painful. A swab was taken and he was given Flucloxacillin. No instruction was given for him to telephone for results. The lab reported Group B Streptococcus that was sensitive to flucloxacillin but at very high doses and recommended changing to amoxicillin. He was not informed of the result, and no change was made to the antibiotics. His condition continued to deteriorate and on 22 December 2007, he was admitted as an emergency. He underwent open debridement, wash out and liner exchange on 22 December 2007, and it was confirmed the infection was ‘as before’ and also present in his blood stream, so he had Group B streptococcal septicaemia. The standards of hygiene in the hospital were very poor, with dirty dressings on windowsills, clean sheets put on top of soiled sheets, and empty hand-sanitizer bottles. Following discharge and review, it was decided the implant needed to come out, and he underwent firststage revision surgery on 1 February 2008. Tissue samples grew coagulase negative staphylococcus, but no Group B strep. He was given IV vancomycin for two weeks and oral linezolid for three weeks. The claimant was discharged in a leg splint and was significantly disabled in his home, which is a Victorian terraced house built on four levels with an upstairs bathroom. He was effectively confined to two rooms downstairs. He underwent second stage of revision surgery on 23 May 2008 and was prescribed prophylactic Cefuroxime peri-operatively, but no intra-operative samples were taken for microscopy and culture. A wound swab taken on 27 May 2008 grew coagulase negative staphylococcus, the same organism found at the time of the first-stage revision surgery, but no further intravenous antibiotics were prescribed. The claimant was discharged on 26 May 2008 with the wound still oozing; it continued to discharge and he was re-admitted on 29 May 2008. A wound swab
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