Effect of Pulmonary Vein Isolation on Quality of Life in Patients with Paroxysmal Atrial Fibrillation

Background: Recent studies have demonstrated that delivering radiofrequency energy to isolate the pulmonary veins (PVs) can cure patients with paroxysmal atrial fibrillation (PAF). Objective: To quantify the effects of radiofrequency catheter isolation of PVs on quality of life (QoL), symptom burden and non-scheduled visiting to physicians in patients with PAF. Methods: Thirty consecutive patients referred for radiofrequency ablation of PAF were included. Questionnaires were administered retrospectively, 6.3 months after the ablation procedure. QoL was measured by the SF-36 (a measure of general health status) and symptoms and health care utilization by a locally constructed questionnaire. Results: Before ablation, patients with PAF had significantly lower scores on all SF-36 subscales with the exception of the pain subscale, compared with a healthy control group. Apart from bodily pain all subscales significantly improved after PV isolation. Twenty patients had an improvement in their total health perception. PV isolation significantly reduced the frequency of episodes of atrial fibrillation (AF) and the proportion of nonscheduled contacts to physicians for AF. Conclusion: QoL in patients with PAF is significantly impaired. PV isolation improves the QoL and reduces the frequency and severity of symptoms and non-scheduled contacts to physicians.