药物免疫毒性:研讨会结论

Drug Information Journal Pub Date : 1996-01-01 DOI:10.1177/009286159603000138

J. W. van der Laan, Jack van der Dean

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引用次数: 1

摘要

4. 对免疫功能测试的适当验证方法表示了一些关注。在使用已知免疫毒物的环形研究中，大多数试验都得到了良好的结果。测定法通常以检测免疫改变的敏感性为特征，无需参考“金标准”*，也需要对免疫的选择性进行验证

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Immunotoxicity of Pharmaceuticals: Conclusions of the Workshop

4. There was some concern expressed over approaches for the proper validation of immune function tests. Most tests have been examined in ring studies using known immunotoxicants with good results. Assays were generally characterized for sensitivity for detecting an immune alteration withOut reference to a “gold standard*” Validation is also necessary with respect to the selectivity of the immune

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来源期刊

Drug Information Journal 医学-卫生保健

自引率

0.00%

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审稿时长

6-12 weeks