疟疾诊断和治疗:尼日利亚阿布贾大都市社区药剂师的看法

Emmanuel Peace Chukwuzurum, Ebenezer Daniel, O. Popoola, P. Abiodun, A. Bello, Kabir Yunusa Amari, CHRISTIE OMOLOLA ADAMS, O. Ojo, O. Olagbegi, Gabriel Omoniyi Ayeni, I. Popoola
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引用次数: 2

摘要

疟疾是一种威胁生命的传染病,是一个重大的全球公共卫生和经济问题。因此,世卫组织建议采取T3行动(检测、治疗和跟踪),以帮助在全球遏制这一祸害。本研究旨在确定疟疾诊断在疟疾病例管理中的功效,以及阿布贾市区社区药师对世卫组织推荐的开始治疗前寄生虫学诊断标准的看法。在阿布贾大都会的207名社区药剂师中进行了一项描述性横断面研究。数据通过结构化、自我管理的问卷获得。调查对象的特征与疟疾检测和治疗的认识、实践和认知之间的关系采用卡方比例分析进行评估。当类别数少于5个时,使用Fisher精确检验。72%(72.9%)的人知道世卫组织建议的疟疾病例管理第三阶段行动。然而,只有不到10%的受访者在这三个方面都接受过培训。在实践中,28.5%的社区药剂师在开始治疗前通过确认性检测进行疟疾诊断。92%(92.3%)仅根据临床体征和症状治疗疟疾。尽管临床诊断率很高,但大多数(84.1%)认为确诊试验在疟疾病例管理中比临床诊断更有效和高效。大多数应答者(60.4%)报告说,最容易获得的确认性检测是mRDT。87%的答复者对疟疾诊断的寄生虫确诊试验有良好的认识,大多数答复者对疟疾确诊试验的结果有信心,68.6%的答复者相信他们的疟疾确诊试验技能。在患者坚持治疗时,略高于一半(52.7%)的答复者不顾确诊试验结果阴性而进行疟疾治疗。与女性相比,男性社区药剂师在治疗前通过确认性检测进行疟疾诊断的比例(39%)更高。对疟疾寄生虫学确证检验效果的认知与年龄、工作经验有显著相关性,工作经验与治疗前确证检验有显著相关性(P<0.05)。从本质上讲,这是呼吁政府、卫生部门的专业机构和所有致力于防治疟疾祸害的人采取行动,以提高公众对世卫组织第三阶段的重要性的认识,并加强一线卫生工作者的能力——社区药房满足社区在疟疾病例管理方面的需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Malaria Diagnosis and Treatment: Perception of Community Pharmacists in Abuja Metropolis, Nigeria
Malaria is a life threatening infectious disease that constitutes a major global public health and economic concern. Consequently, the WHO has recommended a T3 initiative (Test, Treat & Track) to help curb the scourge globally. This study aimed to ascertain the efficacy of malaria diagnosis in malaria case management and perception of community pharmacists on the WHO recommended standard of parasitological diagnosis before commencement of treatment within Abuja metropolis. A descriptive cross sectional study was performed amongst 207 community pharmacists within Abuja Metropolis. Data was obtained through structured, self-administered questionnaire. The association of respondent characteristics with the awareness, practice, and perception of malaria testing, and treatment was evaluated by Chi-square analysis for proportion. Where the number of categories was less than five, Fisher exact test was used. Seventy-two percent (72.9%) were aware of the WHO recommended T3 initiative on malaria case management. However, less than 10% of respondents had training in all the three components. On practice, 28.5% of community pharmacists carry out malaria diagnosis with a confirmatory test before instituting treatment. Ninety-two percent (92.3%) treat malaria based on clinical signs and symptoms only. Despite the high rate of clinical diagnosis, a majority (84.1%) agreed that the confirmatory test is more effective and efficient in malaria case management than clinical diagnosis. Most respondents (60.4%) reported that the confirmatory test most readily available was mRDT. Eighty-seven percent (87%) have good perception on parasitological confirmatory testing for malaria diagnosis and most respondents have confidence in results from the malaria confirmatory test while 68.6% trust their malaria confirmatory test skill. A little above half (52.7%) of the respondents treat for malaria regardless of negative confirmatory test results when the patient insists on treatment. A higher proportion (39%) of male community Pharmacists compared to females carry out malaria diagnosis with a confirmatory test before treatment. There was significant association of perception on the efficacy of a parasitological confirmatory test for malaria with age and work experience and there was significant association of work experience with the practice of confirmatory testing before treatment (P<0.05). Inferentially, this is call to action for government, professional bodies in the health sector and all committed to fight the scourge of malaria for more awareness to the general public on importance of the WHO T3 and capacity strengthening for the frontline health workers – community pharmacy attending to community needs on malaria case management.
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