与印度野生型埃及伊蚊相比,自限型OX513A埃及伊蚊对目前使用的杀虫剂化学物质完全敏感

IF 1.6 Q2 ENTOMOLOGY
Prabhakargouda B Patil, K. Gorman, S. Dasgupta, K. Reddy, Shirish R. Barwale, U. Zehr
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引用次数: 9

摘要

OX513A埃及伊蚊是一种携带自我限制基因的基因工程菌株。几个国家的研究表明,该菌株在减少有害的埃及伊蚊种群方面是有效的。作为与印度环境相关的生物安全评价的一个组成部分,OX513A和两个印度野生型伊蚊。使用世界卫生组织(世卫组织)的检测试剂盒并按照世卫组织的标准测试程序,对埃及伊蚊菌株(来自奥兰加巴德和德里)对印度一系列常用杀虫剂(如二氯二苯三氯乙烷(滴滴涕)、马拉硫磷、溴氰菊酯和氯菊酯)的敏感性进行了测试。分别测定了三种蚊种成虫对所有化合物的敲除时间(KDT)。结果表明,OX513A、奥兰加巴德和德里品系成虫对滴滴涕有抗性,雌雄成虫死亡率分别为90.9%、87.4和44.4%,分别为70.1、3.0和6.0%。相比之下,这三种品系的成虫对马拉硫磷、溴氰菊酯和氯菊酯敏感,死亡率在98%至100%之间。根据KDT50值,与野生型伊蚊相比,OX513A菌株的敏感性更大。对所有杀虫剂检测埃及伊蚊。结果证实,除了对DDT的历史抗性外,OX513A对这些常用化合物保持了完全的敏感性,并表现出与敏感的印度野生型菌株相似的反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Self-Limiting OX513A Aedes aegypti Demonstrate Full Susceptibility to Currently Used Insecticidal Chemistries as Compared to Indian Wild-Type Aedes aegypti
OX513A Aedes aegypti is a genetically engineered strain carrying a self-limiting gene. Studies in several countries have shown the effectiveness of the strain at reducing pest Aedes aegypti populations. As a component of biosafety assessments relevant to Indian environments, OX513A and two Indian wild-type Ae. aegypti strains (from Aurangabad and Delhi) were tested for susceptibility to a range of commonly used insecticides in India, such as dichlorodiphenyltrichloroethane (DDT), malathion, deltamethrin, and permethrin using World Health Organization (WHO) testing kits and following WHO standard test procedures. Knockdown times (KDT) for all compounds were determined separately for male and female adults of the three mosquito strains. Results indicated that adults of OX513A, Aurangabad, and Delhi strains were resistant to DDT, yielding mortality rates of 90.9, 87.4, and 44.4% and 70.1, 3.0, and 6.0% for male and female adults, respectively. In contrast, adults of all three strains were found to be susceptible to malathion, deltamethrin, and permethrin, exhibiting mortalities between 98 and 100%. The magnitudes of susceptibility, based on the KDT50 values, were greater in the OX513A strain, as compared to wild-type strains of Ae. aegypti for all insecticides tested. The results confirm that, aside from historical resistance to DDT, OX513A has retained full sensitivity to these commonly used compounds and exhibits responses akin to those of susceptible Indian wild-type strains.
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来源期刊
CiteScore
1.80
自引率
0.00%
发文量
8
审稿时长
15 weeks
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