{"title":"表观遗传学与肿瘤微环境的结合","authors":"P. Dey","doi":"10.1159/000354283","DOIUrl":null,"url":null,"abstract":"It is known that tumor cells undergo genetic and epigenetic alterations. Recent evidence suggests that epigenetic changes in the tumor microenvironment play a significant role in carcinogenesis. In this brief review, we discuss the epigenetic changes of the microenvironment in different malignancies and their clinical significance.","PeriodicalId":90260,"journal":{"name":"Medical epigenetics","volume":"1 1","pages":"31 - 36"},"PeriodicalIF":0.0000,"publicationDate":"2013-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000354283","citationCount":"6","resultStr":"{\"title\":\"Epigenetics Meets the Tumor Microenvironment\",\"authors\":\"P. Dey\",\"doi\":\"10.1159/000354283\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"It is known that tumor cells undergo genetic and epigenetic alterations. Recent evidence suggests that epigenetic changes in the tumor microenvironment play a significant role in carcinogenesis. In this brief review, we discuss the epigenetic changes of the microenvironment in different malignancies and their clinical significance.\",\"PeriodicalId\":90260,\"journal\":{\"name\":\"Medical epigenetics\",\"volume\":\"1 1\",\"pages\":\"31 - 36\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-08-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000354283\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical epigenetics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000354283\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical epigenetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000354283","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
It is known that tumor cells undergo genetic and epigenetic alterations. Recent evidence suggests that epigenetic changes in the tumor microenvironment play a significant role in carcinogenesis. In this brief review, we discuss the epigenetic changes of the microenvironment in different malignancies and their clinical significance.
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