人免疫球蛋白Lambda (IGL)基因命名法

M. Lefranc
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引用次数: 68

摘要

“人类免疫球蛋白Lambda (IGL)基因命名法”是“IMGT基因座焦点”部分的第18篇报告,提供了所有人类IGL基因的第一个完整列表。每个单倍体基因组的IGL基因总数为87-96个(如果包括孤儿,则为93-102个),其中37-43个基因是功能性的。第22q11.2号染色体上的人类IGL基因和第8、22号染色体上的IGL孤儿的IMGT/Human Genome Organization (HUGO)基因名称和定义,根据IMGT Scientific chart的规则,提供基因功能和等位基因数量,IMGT参考序列的加入号和基因组数据库GDB和NCBI LocusLink数据库的加入ID,其中已输入所有IMGT人类IGL基因。这些表格可在国际免疫遗传学数据库IMGT的IMGT Marie-Paule页面(http://imgt.cines.fr)上获得,该数据库由法国蒙彼利埃第二大学的Marie-Paule Lefranc创建。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nomenclature of the Human Immunoglobulin Lambda (IGL) Genes
‘Nomenclature of the Human Immunoglobulin Lambda (IGL) Genes’, the 18th report of the ‘IMGT Locus in Focus’ section, provides the first complete list of all the human IGL genes. The total number of human IGL genes per haploid genome is 87–96 (93–102 if the orphons are included), of which 37–43 genes are functional. IMGT/Human Genome Organization (HUGO) gene names and definitions of the human IGL genes on chromosome 22q11.2 and IGL orphons on chromosomes 8 and 22 are provided with the gene functionality and the number of alleles, according to the rules of the IMGT Scientific chart, with the accession numbers of the IMGT reference sequences and with the accession ID of the Genome Database GDB and NCBI LocusLink databases, in which all the IMGT human IGL genes have been entered. The tables are available at the IMGT Marie-Paule page of IMGT, the international ImMunoGeneTics database (http://imgt.cines.fr) created by Marie-Paule Lefranc, Université Montpellier II, CNRS, France.
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