Łukasz Szymański, Damian Matak, E. Bartnik, C. Szczylik, A. Czarnecka
{"title":"甲状腺激素作为肾细胞癌的调节因子","authors":"Łukasz Szymański, Damian Matak, E. Bartnik, C. Szczylik, A. Czarnecka","doi":"10.1155/2016/1362407","DOIUrl":null,"url":null,"abstract":"It is known that thyroid hormone is an important regulator of cancer development and metastasis. What is more, changes across the genome, as well as alternative splicing, may affect the activity of the thyroid hormone receptors. Mechanism of action of the thyroid hormone is different in every cancer; therefore in this review thyroid hormone and its receptor are presented as a regulator of renal cell carcinoma.","PeriodicalId":89176,"journal":{"name":"Journal of signal transduction","volume":"2016 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/1362407","citationCount":"11","resultStr":"{\"title\":\"Thyroid Hormones as Renal Cell Cancer Regulators\",\"authors\":\"Łukasz Szymański, Damian Matak, E. Bartnik, C. Szczylik, A. Czarnecka\",\"doi\":\"10.1155/2016/1362407\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"It is known that thyroid hormone is an important regulator of cancer development and metastasis. What is more, changes across the genome, as well as alternative splicing, may affect the activity of the thyroid hormone receptors. Mechanism of action of the thyroid hormone is different in every cancer; therefore in this review thyroid hormone and its receptor are presented as a regulator of renal cell carcinoma.\",\"PeriodicalId\":89176,\"journal\":{\"name\":\"Journal of signal transduction\",\"volume\":\"2016 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-03-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1155/2016/1362407\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of signal transduction\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2016/1362407\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of signal transduction","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2016/1362407","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
It is known that thyroid hormone is an important regulator of cancer development and metastasis. What is more, changes across the genome, as well as alternative splicing, may affect the activity of the thyroid hormone receptors. Mechanism of action of the thyroid hormone is different in every cancer; therefore in this review thyroid hormone and its receptor are presented as a regulator of renal cell carcinoma.
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