择期骨科大手术患者术前贫血和血凝缺乏症的发生率

E. Bisbe, J. Castillo, M. Sáez, X. Santiveri, A. Ruiz, M. Muñoz
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引用次数: 47

摘要

术前贫血是大骨科手术(MOS)患者异基因输血的独立危险因素,而血液病缺乏可延迟术后贫血的恢复。然而,这两种情况都可以在采取选择性程序之前加以纠正。因此,我们评估了MOS患者中贫血和血液缺乏的患病率。2001年1月至2002年12月,从同一家机构收集了所有MOS患者的人口统计和实验室数据。共有715名患者(483名女性/232名男性)进入研究。根据世卫组织的标准,贫血的患病率为10.5%,并随着年龄的增长而增加,没有性别差异。19.4%的患者术前血红蛋白< 13 g/dL, 33%的患者缺铁,12.3%的患者缺维生素B12, 3%的患者缺叶酸。在贫血患者中,30.8%为缺血性贫血(20%为缺铁性贫血),30.8%为慢性病性贫血,38.4%为混合性或不明原因性贫血。在MOS患者中,贫血和血液缺乏症的发生率很高。因此,只要有可能,接受MOS的患者应尽早评估,以便在预定手术之前进行适当的调查和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of preoperative anemia and hematinic deficiencies in patients scheduled for elective major orthopedic surgery
SUMMARY Preoperative anemia is an independent risk factor for allogeneic blood transfusion in patients undergoing major orthopedic surgery (MOS) whereas hematinic deficiency can delay the recovery from postoperative anemia. Both conditions can, however, be corrected before elective procedures are undertaken. We therefore evaluated the prevalence of anemia and hematinic deficiencies in MOS patients. Demographic and laboratory data were gathered from all MOS patients from a single institution between January 2001 and December 2002. A total of 715 patients (483 women/232 men) entered the study. According to WHO criteria, the prevalence of anemia was 10.5% and increased with age, without gender-related differences. Preoperative hemoglobin was < 13 g/dL in 19.4% of patients, and the prevalence of hematinic deficiencies was 33% for iron, 12.3% for vitamin B12 and 3% for folate. In anemic patients, there were 30.8% with hematinic deficiency anemia (20% with iron-deficiency anemia), 30.8% with anemia of chronic disease and 38.4% with anemia of mixed or indeterminate cause. The prevalence of anemia, as well as of hematinic deficiencies, is high in MOS patients. Therefore, whenever possible, patients undergoing MOS should be assessed early enough to allow for proper investigation and treatment prior to the scheduled procedure.
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