麻醉和草药补充剂

T. A. Danloff
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引用次数: 1

摘要

草药补充剂的使用正在增加。22%至34%的术前成年人承认服用过这些药物。多达五分之一的患者在服用处方药的同时服用草药补充剂。Blanck等人发现,61%的慢性疾病患者没有与医生讨论他们使用膳食草药补充剂的情况。此外,70%的术前成年人即使在麻醉前评估时被特别询问也没有透露他们使用草药补充剂(补充数字内容1,http://links.lww.com/ASA/A189)。在601名接受门诊手术的儿童中,10.1%过去曾服用草药补充剂,6.4%目前正在服用草药。其中,85%的父母没有告诉他们孩子的医生关于补充剂的事,90%没有告诉他们的手术团队(补充数字内容2,http://links.lww.com/ASA/A190)。在接受调查的服用草药补充剂的儿童中,16%的人服用了可能影响围手术期护理的草药。在一项对产妇的调查中,15%的人在服用草药补充剂,其中41%的人不认为这些补充剂是药物。由于患者通常不将草药补充剂视为药物,因此在获取病史时特别询问它们是非常重要的(补充数字内容3,http://links.lww.com/ASA/A191)。《膳食补充剂健康与教育法》于1994年在美国成为法律。这是对《联邦食品、药品和化妆品法》的一项修正案,规定制造商,而不是食品和药物管理局(FDA),对补充剂的安全负责。膳食补充剂在法律上被认为是“食物”,而不是药物(补充数字内容4,http://links.lww.com/ASA/A192)。它们包括维生素、矿物质、草药或其他植物药、氨基酸、浓缩物、代谢物、成分、提取物,或“人类通过增加总膳食摄入量来补充饮食的膳食物质”(例如,酶或器官或腺体组织)。所有补充剂都附有以下免责声明:“本声明未经FDA评估。本产品不用于诊断、治疗、治愈或预防任何疾病。不管补充剂的药理作用如何,根据《膳食补充剂健康与教育法》,只有药物才能合法地宣称这种功效。所有在膳食补充剂健康和教育法颁布之前销售的补充剂都包括在内,不需要fda批准
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anesthesia and Herbal Supplements
The use of herbal supplements is on the rise. From 22 to 34% of preoperative adults admit to taking them. As many as one in five patients use herbal supplements while taking prescription medication. Blanck et al. found that 61% of patients with a chronic disease did not discuss their use of dietary herbal supplements with their physicians. Furthermore, 70% of preoperative adults did not disclose their use of herbal supplements even when specifically asked during their preanesthetic assessment (Supplemental Digital Content 1, http://links.lww.com/ASA/A189). Of 601 children presenting for ambulatory surgery, 10.1% had taken herbal supplements in the past and 6.4% were taking herbs currently. Of these, 85% of the parents had not told their child’s physician about the supplements and 90% had not told their surgical team (Supplemental Digital Content 2, http://links.lww.com/ASA/A190). Among children in this survey who were taking herbal supplements, 16% were using herbs that could impact perioperative care. In a survey of parturients, 15% were using herbal supplements and 41% of these patients did not think of the supplements as drugs. Because patients often do not view herbal supplements as drugs, it is very important to ask about them specifically when obtaining a history (Supplemental Digital Content 3, http://links.lww.com/ASA/A191). The Dietary Supplement Health and Education Act became law in the United States in 1994. It is an amendment to the Federal Food, Drug and Cosmetic Act and states that the manufacturer, not the Food and Drug Administration (FDA), is responsible for the safety of the supplement. Dietary supplements are legally considered ‘‘foods,’’ not drugs (Supplemental Digital Content 4, http://links.lww.com/ASA/A192). They include vitamins, minerals, herbs or other botanicals, amino acids, concentrates, metabolites, constituents, extracts, or ‘‘a dietary substance for use by man to supplement the diet by increasing the total dietary intake (e.g., enzymes or tissues from organs or glands).’’ All supplements carry the following disclaimer: ‘‘This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.’’ Regardless of the pharmacological action of the supplement, according to the Dietary Supplement Health and Education Act, only a drug can legally make that claim. All supplements marketed before the Dietary Supplement Health and Education Act are included and do not need approval from the
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