肾移植急性体液性排斥反应的针芯活检诊断——附病理形态学回顾1例

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AJSP-Reviews and Reports Pub Date : 2015-11-01 DOI:10.1097/PCR.0000000000000112

J. Aufman

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引用次数: 0

摘要

摘要:穿刺活检是评估移植肾的重要方法。通过检查形态学结果，病理学家可以告知肾科医生某些发现，这些发现有助于指导治疗管理，以延长移植肾的生命。肾内科医生一旦发现肾功能不全的体征和症状，通常就会决定是否进行肾活检，因此，大多数移植肾的活检通常有某种形态病理学，由于早期排斥反应的急性意识，这可能是最小的。本文综述了急性抗体介导的排斥反应的历史和移植肾幽默性排斥反应的形态学发现。

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Transplant Kidney With Acute Humoral Rejection Diagnosed by Needle Core Biopsy—A Case Report With Review of Pathological Morphology

Abstract Needle core biopsy is an important procedure used to evaluate transplanted kidneys. By examining the morphological findings, the pathologist can inform the nephrologist of certain findings that help guide the therapeutic management to prolong the life of the transplant kidney. The request for a kidney biopsy is usually decided as soon as signs and symptoms of renal dysfunction are noticed by the nephrologist, and therefore, most biopsies of the transplanted kidneys usually have some type of morphological pathology, which may be minimal because of the acute awareness of early rejection. This review discusses the history of acute antibody-mediated rejection and the morphological findings seen in humor rejection of the transplanted kidney.

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来源期刊

AJSP-Reviews and Reports PATHOLOGY-

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期刊介绍： Each issue of Pathology Case Reviews examines one vital theme in the field with peer-reviewed, clinically oriented case reports that focus on diagnosis, specimen handling and reports generation. Each theme-oriented issue covers both histopathologic and cytopathologic cases, offering a comprehensive perspective that includes editorials and review articles of the newest developments in the field, differential diagnosis hints, applications of new technologies, reviews of current issues and techniques and an emphasis on new approaches.