{"title":"单克隆药物治疗癌症的不良反应","authors":"Christopher M. Jones, J. Pascoe, J. Coleman","doi":"10.1097/FAD.0b013e32835ccbf1","DOIUrl":null,"url":null,"abstract":"SummaryMonoclonal agents have been developed to specifically target cancer cells but they can have systemic adverse effects which can be life-threatening, particularly infusion reactions, immunosuppression, tumour lysis syndrome, profound hypertension, cardiac failure and haematological toxicity.","PeriodicalId":39261,"journal":{"name":"Adverse Drug Reaction Bulletin","volume":"277 1","pages":"1067–1070"},"PeriodicalIF":0.0000,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/FAD.0b013e32835ccbf1","citationCount":"0","resultStr":"{\"title\":\"Adverse reactions to monoclonal agents used in the treatment of cancer\",\"authors\":\"Christopher M. Jones, J. Pascoe, J. Coleman\",\"doi\":\"10.1097/FAD.0b013e32835ccbf1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"SummaryMonoclonal agents have been developed to specifically target cancer cells but they can have systemic adverse effects which can be life-threatening, particularly infusion reactions, immunosuppression, tumour lysis syndrome, profound hypertension, cardiac failure and haematological toxicity.\",\"PeriodicalId\":39261,\"journal\":{\"name\":\"Adverse Drug Reaction Bulletin\",\"volume\":\"277 1\",\"pages\":\"1067–1070\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1097/FAD.0b013e32835ccbf1\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Adverse Drug Reaction Bulletin\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/FAD.0b013e32835ccbf1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Adverse Drug Reaction Bulletin","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/FAD.0b013e32835ccbf1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Adverse reactions to monoclonal agents used in the treatment of cancer
SummaryMonoclonal agents have been developed to specifically target cancer cells but they can have systemic adverse effects which can be life-threatening, particularly infusion reactions, immunosuppression, tumour lysis syndrome, profound hypertension, cardiac failure and haematological toxicity.
期刊介绍:
For over 40 years, Adverse Drug Reaction Bulletin has provided comprehensive coverage in the field of adverse drug reactions. Each issue contains an invited article on a topic of current interest, dealing with specific conditions from drug-induced lung disorders to drug-induced sexual dysfunction, or types of drugs from lipid-lowering agents to poisons antidotes. This bimonthly journal"s articles are timely, succinct and fully referenced