成人注意缺陷多动障碍的兴奋剂药物治疗:心血管效应和心源性猝死的风险

Q4 Medicine

Adverse Drug Reaction Bulletin Pub Date : 2016-08-01 DOI:10.1097/FAD.0000000000000019

M. Pucci

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引用次数: 1

摘要

治疗注意力缺陷多动障碍的药物越来越多地被用于成人。人们一直担心兴奋剂治疗注意力缺陷多动障碍药物的心血管安全性。总体而言，对成人的研究显示，心率、舒张压和收缩压的增加幅度不大，但在统计学上有显著意义，但时间相对较短。流行病学研究尚未明确表明心脏性猝死风险增加，但不能排除风险小幅增加的可能性。

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Stimulant pharmacotherapy for adults with attention deficit hyperactivity disorder: cardiovascular effects and risk of sudden cardiac death

SummaryDrugs for attention deficit hyperactivity disorder are increasingly being used in adults. There have been concerns about the cardiovascular safety of stimulant attention deficit hyperactivity disorder drugs. Overall, studies in adults have shown small but statistically significant increases in heart rate and DBP and SBP, but have been relatively short term. Epidemiological studies have not clearly demonstrated an increased risk of sudden cardiac death, but a small increase in the risk cannot be ruled out.

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来源期刊

Adverse Drug Reaction Bulletin Medicine-Pharmacology (medical)

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： For over 40 years, Adverse Drug Reaction Bulletin has provided comprehensive coverage in the field of adverse drug reactions. Each issue contains an invited article on a topic of current interest, dealing with specific conditions from drug-induced lung disorders to drug-induced sexual dysfunction, or types of drugs from lipid-lowering agents to poisons antidotes. This bimonthly journal"s articles are timely, succinct and fully referenced