Erectile Dysfunction: Science and Medicine

Abstract Much progress has been made over the past 20 years in the science and medicine of erectile dysfunction. Advances in knowledge of the basic mechanisms of penile erection and that associated with its pathophysiology have been impressively translated into an expanding range of therapies, which have increasingly enabled natural erectile responses. Despite this progress, ideal interventions for erectile dysfunction should fully restore natural erectile ability without the need for repeated treatments. Progress in the field is expected to address this limitation and to arise from new discoveries of erectile mechanisms and novel approaches to deliver corrective therapy.