{"title":"癌症患者的阿片类药物转换","authors":"S. Mercadante","doi":"10.1080/23809000.2016.1258303","DOIUrl":null,"url":null,"abstract":"ABSTRACT Introduction: The substitution of another opioid for a previous one in order to improve the clinical response has largely been reported as opioid switching, aimed to improve the opioid response in different clinical conditions. Areas covered: Existing data from literature have been reviewed to cover the different aspects of opioid switching in cancer patients. Expert commentary: Opioid switching has been reported to produce a clinical improvement in a large number of patients with chronic cancer pain presenting a poor response to one opioid. Despite the favourable effects reported with opioid switching, data are based on open studies, most of them being retrospective or small case series.","PeriodicalId":91681,"journal":{"name":"Expert review of quality of life in cancer care","volume":"1 1","pages":"443 - 447"},"PeriodicalIF":0.0000,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23809000.2016.1258303","citationCount":"0","resultStr":"{\"title\":\"Opioid switching in cancer patients\",\"authors\":\"S. Mercadante\",\"doi\":\"10.1080/23809000.2016.1258303\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABSTRACT Introduction: The substitution of another opioid for a previous one in order to improve the clinical response has largely been reported as opioid switching, aimed to improve the opioid response in different clinical conditions. Areas covered: Existing data from literature have been reviewed to cover the different aspects of opioid switching in cancer patients. Expert commentary: Opioid switching has been reported to produce a clinical improvement in a large number of patients with chronic cancer pain presenting a poor response to one opioid. Despite the favourable effects reported with opioid switching, data are based on open studies, most of them being retrospective or small case series.\",\"PeriodicalId\":91681,\"journal\":{\"name\":\"Expert review of quality of life in cancer care\",\"volume\":\"1 1\",\"pages\":\"443 - 447\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/23809000.2016.1258303\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Expert review of quality of life in cancer care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/23809000.2016.1258303\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Expert review of quality of life in cancer care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/23809000.2016.1258303","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ABSTRACT Introduction: The substitution of another opioid for a previous one in order to improve the clinical response has largely been reported as opioid switching, aimed to improve the opioid response in different clinical conditions. Areas covered: Existing data from literature have been reviewed to cover the different aspects of opioid switching in cancer patients. Expert commentary: Opioid switching has been reported to produce a clinical improvement in a large number of patients with chronic cancer pain presenting a poor response to one opioid. Despite the favourable effects reported with opioid switching, data are based on open studies, most of them being retrospective or small case series.