癌症患者的阿片类药物转换

S. Mercadante
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引用次数: 0

摘要

摘要:为了改善临床反应,以另一种阿片类药物替代前一种阿片类药物已被广泛报道为阿片类药物转换,旨在改善不同临床条件下的阿片类药物反应。涵盖的领域:已经审查了文献中的现有数据,以涵盖癌症患者阿片类药物转换的不同方面。专家评论:据报道,阿片类药物转换对大量对一种阿片类药物反应不佳的慢性癌症疼痛患者产生临床改善。尽管阿片类药物转换报告了有利的效果,但数据是基于公开研究,其中大多数是回顾性的或小病例系列。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Opioid switching in cancer patients
ABSTRACT Introduction: The substitution of another opioid for a previous one in order to improve the clinical response has largely been reported as opioid switching, aimed to improve the opioid response in different clinical conditions. Areas covered: Existing data from literature have been reviewed to cover the different aspects of opioid switching in cancer patients. Expert commentary: Opioid switching has been reported to produce a clinical improvement in a large number of patients with chronic cancer pain presenting a poor response to one opioid. Despite the favourable effects reported with opioid switching, data are based on open studies, most of them being retrospective or small case series.
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