S. Siddique, Shamma Firdous, A. Durrani, Shaista Khan, A. Saeed
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Hesperidin, a citrus flavonoid, increases the bioavailability of micronutrients of Gallus domesticus (chicken) eggshell: in vitro study
Abstract The consumption of citrus flavonoid, hesperidin may inhibit the bone loss. The purpose of this study was to evaluate the effect of hesperidin on the bioavailability of Ca, a probable reason to prevent bone loss. Citrus flavonoid (hesperidin) in combination with citric acid and ascorbic acid was scrutinized to estimate the bioavailability of micronutrients from chicken egg shells using in vitro method. Effect of citric acid, ascorbic acid and hesperidin on the bioavailability of minerals (Zn, Fe) and macro elements (Ca, Mg, P) was evaluated and the amounts required to get maximum bioavailability were concluded. The highest bioavailability of Ca, Mg, P, Fe and Zn was 89.25 ± 2.13, 92.28 ± 1.87, 40.32 ± 3.09, 32.81 ± 1.24 and 46.19 ± 0.83%, respectively after the addition of 3 g of citric acid, 100 mg of ascorbic acid and 4 mg of hesperidin per gram of chicken eggshell powder. Citric acid greatly affects the bioavailability of Ca, Mg, P, and Zn, whereas addition of ascorbic acid enhances the bioavailability of Fe, and hesperidin boosts the bioavailability (p < 0.05) of all micronutrients of the chicken eggshells.
期刊介绍:
Chemical Speciation & Bioavailability ( CS&B) is a scholarly, peer-reviewed forum for insights on the chemical aspects of occurrence, distribution, transport, transformation, transfer, fate, and effects of substances in the environment and biota, and their impacts on the uptake of the substances by living organisms. Substances of interests include both beneficial and toxic ones, especially nutrients, heavy metals, persistent organic pollutants, and emerging contaminants, such as engineered nanomaterials, as well as pharmaceuticals and personal-care products as pollutants. It is the aim of this Journal to develop an international community of experienced colleagues to promote the research, discussion, review, and spread of information on chemical speciation and bioavailability, which is a topic of interest to researchers in many disciplines, including environmental, chemical, biological, food, medical, toxicology, and health sciences.
Key themes in the scope of the Journal include, but are not limited to, the following “6Ms”:
Methods for speciation analysis and the evaluation of bioavailability, especially the development, validation, and application of novel methods and techniques.
Media that sustain the processes of release, distribution, transformation, and transfer of chemical speciation; of particular interest are emerging contaminants, such as engineered nanomaterials, pharmaceuticals, and personal-care products.
Mobility of substance species in environment and biota, either spatially or temporally.
Matters that influence the chemical speciation and bioavailability, mainly environmentally relevant conditions.
Mechanisms that govern the transport, transformation, transfer, and fate of chemical speciation in the environment, and the biouptake of substances.
Models for the simulation of chemical speciation and bioavailability, and for the prediction of toxicity.
Chemical Speciation & Bioavailability is a fully open access journal. This means all submitted articles will, if accepted, be available for anyone to read, anywhere, at any time. immediately on publication. There are no charges for submission to this journal.