脉冲染料激光治疗糖尿病脂质坏死性坏死

G. Moreno‐Arias, A. Camps‐Fresneda
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引用次数: 26

摘要

背景与目的:不同的治疗方式已被提倡,但临床反应是不可预测的。本研究的目的是评估脉冲染料激光(Candela SPTLÁ, Irvine, MA, USA)在治疗非糖尿病患者腿前部直径为4厘米的脂质坏死区域中的有效性。材料与方法:在6.0、6.5和7.0 J/ cm2能量影响下进行点试验,术后2个月评估后选择最佳能量影响。患者接受三次治疗,治疗剂量为6.5 J/ cm2,波长为585 nm,光斑尺寸为5 mm,脉冲时间为450µs,间隔为8周。患者被给予常规护肤建议,使用润肤霜和防晒霜(SPF 15),直到下一个疗程。结果:整体美容得到改善,红斑和毛细血管扩张减少,左半病变的进展(大小)稳定,没有萎缩或色素改变的改变。右上象限病变表现为红斑周围晕,红斑和毛细血管扩张轻微减少,离散大小增加。结论:脉冲染料激光可有效改善脂质坏死毛细血管扩张及红斑成分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Necrobiosis lipoidica diabeticorum treated with the pulsed dye laser
BACKGROUND AND OBJECTIVE : Different treatment modalities have been advocated for necrobiosis lipoidica diabeticorum but clinical response is unpredictable. The purpose of this study was to evaluate the usefulness of pulsed dye laser (Candela SPTLÁ, Irvine, MA, USA) in the treatment of an area of necrobiosis lipoidica of 4 cm in diameter on the anterior aspect of the leg in a non-diabetic patient. MATERIALS AND METHODS : A spot test was made at 6.0, 6.5 and 7.0 J/cm 2 energy fluences and the best energy fluence was selected after a 2-month postoperative evaluation. The patient received three treatment sessions with a fluence of 6.5 J/cm 2 , 585-nm wavelength, 5-mm spot size, and 450 µs pulse duration at 8-week intervals. The patient was given routine skin care advice with emollient cream and sunscreen (SPF 15) until the following session. RESULTS : Overall cosmetic improvement was achieved, with a decrease of erythema and telangiectasis, and stabilization in terms of progression (size) in the left half of the lesion, with no modification of atrophy or pigmentary changes. The right upper quadrant of the lesion showed an erythematous peripheral halo with minimal reduction in the erythema and telangiectasia, and discrete size increase. CONCLUSION : Pulsed dye laser may be a useful treatment for improving the telangiectasia and erythematous component of necrobiosis lipoidica.
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